{"id":"W2913213049","doi":"10.1016/j.celrep.2019.01.054","title":"Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Dental and Craniofacial Research; National Institute of Allergy and Infectious Diseases; European Research Council; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"Citrobacter rodentium; Colitis; Citrobacter; Integrin; Macrophage; Biology; Immunology; Microbiology; Enterobacteriaceae; Biochemistry; Escherichia coli; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002802332,0.0003411854,0.0005041508,0.00007628139,0.0002510237,0.00004430531,0.0001521299,0.0005341477,0.001294585],"category_scores_gemma":[0.000053689,0.0003100564,0.0001326243,0.00009783597,0.0001068232,0.0001466075,0.0002150359,0.0005584957,0.0006160671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006098222,"about_ca_system_score_gemma":0.0001112614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008499894,"about_ca_topic_score_gemma":0.00004333646,"domain_scores_codex":[0.9977892,0.0001752463,0.0005413272,0.0008125131,0.00007839749,0.0006033334],"domain_scores_gemma":[0.998687,0.00005833604,0.0003503705,0.0007406875,0.00009078093,0.00007277416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009725552,0.00009697976,0.004024945,0.00004541633,0.00009219162,0.0004942887,0.0004791068,3.06943e-7,0.9876952,0.000018212,0.006144525,0.0008115458],"study_design_scores_gemma":[0.0009371061,0.0001971125,0.01709296,0.00005212177,0.00005134283,0.0007454261,0.0001209349,0.000001809156,0.8120654,0.0002500434,0.1681034,0.0003823103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797354,0.0007199466,0.00003905272,0.00003145706,0.002187107,0.0007356053,0.0006719771,0.0001233555,0.01575606],"genre_scores_gemma":[0.961262,0.00005840902,0.00005162716,0.0001036657,0.00008149652,0.00003890445,0.0004580061,0.000046695,0.03789919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1756298,"threshold_uncertainty_score":0.9999352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005672056313850024,"score_gpt":0.1863986809123817,"score_spread":0.1807266245985316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}