{"id":"W2913251193","doi":"10.1002/jimd.12018","title":"Fetal gene therapy for neurodegenerative lysosomal storage diseases","year":2019,"lang":"en","type":"letter","venue":"Journal of Inherited Metabolic Disease","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Medical Research Council Canada; Medical Research Council; National Institute for Health and Care Research","keywords":"Medicine; Library science; Gene transfer; Gerontology; Gene; Genetics; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002398589,0.0006138824,0.00154754,0.0006784527,0.0001119477,0.0001124122,0.000492561,0.0003558094,0.0002689164],"category_scores_gemma":[0.0005099681,0.0004757598,0.001833807,0.0003689244,0.0001849665,0.0001547815,0.00007834857,0.001572474,0.00002489803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005467524,"about_ca_system_score_gemma":0.0020647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003236178,"about_ca_topic_score_gemma":1.694229e-7,"domain_scores_codex":[0.9959016,0.0003968894,0.0009148062,0.0005801618,0.001497828,0.0007086699],"domain_scores_gemma":[0.9964744,0.0002016044,0.0007150266,0.000770945,0.001147323,0.0006906372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004535316,0.0009440445,0.001214616,0.000646404,0.001808914,0.004102518,0.0000573577,0.00006245705,0.008063922,0.00001036561,0.9694173,0.00913673],"study_design_scores_gemma":[0.007652346,0.0009480612,0.01856386,0.0001590498,0.001888117,0.0002096495,0.00001917967,0.000164734,0.0006365905,0.00006669058,0.9692576,0.0004341194],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.323971,0.1921251,0.001645109,0.4704864,0.003163705,0.005980022,0.002337091,0.00008270126,0.0002088585],"genre_scores_gemma":[0.01830263,0.02388396,0.00149406,0.9190608,0.02441667,0.0002936665,0.001491055,0.0006391861,0.01041797],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.4485744,"threshold_uncertainty_score":0.9997694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02943736584585658,"score_gpt":0.3030248255108565,"score_spread":0.2735874596649999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}