{"id":"W2913262567","doi":"10.1017/erm.2018.7","title":"Structure, regulation and related diseases of the actin-binding protein gelsolin","year":2018,"lang":"en","type":"review","venue":"Expert Reviews in Molecular Medicine","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Chiropractic Association","funders":"","keywords":"Gelsolin; Actin; Actin-binding protein; Cell biology; Plasma protein binding; Chemistry; Biophysics; Biology; Actin cytoskeleton; Cytoskeleton; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001841587,0.0004400134,0.0005377798,0.001058847,0.0002268808,0.0005707912,0.0003594482,0.0006260676,0.002495146],"category_scores_gemma":[0.0002475938,0.0001583116,0.0002819381,0.000723224,0.0002518439,0.0005741956,0.000447454,0.00085542,0.001577703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004078745,"about_ca_system_score_gemma":0.0005101371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007000914,"about_ca_topic_score_gemma":0.000979569,"domain_scores_codex":[0.9999191,0.00001055897,0.00001036211,0.00001695611,0.00003132238,0.00001172161],"domain_scores_gemma":[0.9999318,0.00002068831,0.00001557945,0.000002523062,0.00001967383,0.000009715411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001151002,0.00006394835,0.0002862295,0.01692026,0.00008393949,0.0004682329,0.000101345,0.0005040083,0.01816758,0.009324323,0.04006563,0.9138994],"study_design_scores_gemma":[0.000008813471,0.00005334058,0.0008986812,0.001078566,0.00005412577,0.001773231,0.00003171964,0.00009985052,0.002769491,0.002094207,0.9911243,0.00001370112],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003556634,0.9976864,0.0001713191,0.0002494954,0.0001510534,0.000003296362,0.00002882289,0.000008490892,0.001345458],"genre_scores_gemma":[0.002624612,0.994991,0.000241859,0.0001734019,0.0001501192,0.000006989964,0.00005857846,0.000002804974,0.001750566],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002495146,"threshold_uncertainty_score":0.008347094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02164662519787718,"score_gpt":0.3283955761974932,"score_spread":0.306748950999616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}