{"id":"W2913288555","doi":"10.1172/jci120412","title":"Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad","keywords":"Neurogenesis; Hippocampal formation; Neuroscience; Stroke (engine); Hippocampus; Forgetting; Psychology; Memory impairment; Memantine; Neural stem cell; Cognition; Doublecortin; Medicine; Dentate gyrus; Dementia; Internal medicine; Biology; Disease; Stem cell; Cognitive psychology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009864629,0.000146086,0.000498513,0.0002336534,0.00002046523,0.00002567059,0.0001670996,0.0000994561,0.00006391668],"category_scores_gemma":[0.00206085,0.0001227615,0.0002317056,0.0003200365,0.0001400392,0.000335783,0.0000427606,0.0003362724,0.00004125115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001608986,"about_ca_system_score_gemma":0.000145157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000053394,"about_ca_topic_score_gemma":0.000003199543,"domain_scores_codex":[0.9965234,0.0007828742,0.001694756,0.0002816342,0.0005267568,0.0001905783],"domain_scores_gemma":[0.9964982,0.001719409,0.001274991,0.0001127852,0.0002190547,0.0001755666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007889305,0.0003312037,0.07260537,0.00004113172,0.000008522323,0.00007285614,0.00009211974,0.0001330025,0.9251871,0.0002480424,0.00001413222,0.0004775815],"study_design_scores_gemma":[0.001284954,0.001167155,0.2152681,0.0001655996,0.00003831213,0.00003947072,0.00003560489,0.0005740952,0.7808842,0.0004350272,0.0000210196,0.00008644883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984786,0.0000320691,0.00007794258,0.0001933767,0.00088681,0.0002546287,0.00002240751,0.000007616088,0.00004652819],"genre_scores_gemma":[0.9980422,0.0001829675,0.0001838356,0.001405617,0.0001261137,0.000004736262,7.256723e-7,0.00001850482,0.0000352746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1443029,"threshold_uncertainty_score":0.5006068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06731522080757667,"score_gpt":0.341246545330423,"score_spread":0.2739313245228463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}