{"id":"W2913290054","doi":"10.1182/blood-2018-99-110798","title":"Bosutinib or Imatinib in Older Vs Younger Patients with Newly Diagnosed Chronic Myeloid Leukemia in the Phase 3 BFORE Trial","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Bosutinib; Medicine; Imatinib; Internal medicine; Population; Adverse effect; Myeloid leukemia; Imatinib mesylate; Surgery; Oncology; Gastroenterology; Nilotinib","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001206019,0.0004221588,0.001000584,0.0001107553,0.0001998714,0.0004803799,0.0001939557,0.000389233,0.002529605],"category_scores_gemma":[0.0006415081,0.0001082342,0.0007863715,0.0001872646,0.0001809391,0.0003892068,0.0002563159,0.001137865,0.0002235289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002648505,"about_ca_system_score_gemma":0.0003938182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003899624,"about_ca_topic_score_gemma":0.001372273,"domain_scores_codex":[0.9997501,0.0001305659,0.00001559188,0.00003941694,0.0000230912,0.00004118112],"domain_scores_gemma":[0.9995468,0.00007790523,0.000150617,0.00002288739,0.0000202233,0.0001814842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8780785,0.004129609,0.03077048,0.0009083552,0.002698699,0.0001973908,0.0001057963,0.0008997904,0.01039443,0.0003691241,0.005750075,0.06569771],"study_design_scores_gemma":[0.5646623,0.1781636,0.2338103,0.0003523094,0.003670457,0.0007976919,0.000132599,0.00180455,0.001920894,0.0009360737,0.01367829,0.00007094694],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910329,0.005619806,0.0001216435,0.0004891222,0.000108975,0.0002212083,0.0008534596,0.00001818223,0.001534792],"genre_scores_gemma":[0.9925318,0.002196955,0.0002988603,0.001229114,0.0002773369,0.0003701684,0.002059175,0.000006761687,0.001029821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002529605,"threshold_uncertainty_score":0.00846231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01533459692088097,"score_gpt":0.2850522063213096,"score_spread":0.2697176094004286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}