{"id":"W2913322643","doi":"10.1182/blood-2018-99-115370","title":"Slit-Robo Pathway Is Clinically Relevant and May Represent a Potential Target in Acute Promyelocytic Leukemia","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Acute promyelocytic leukemia; Cancer research; Arsenic trioxide; Annexin A5; Promyelocytic leukemia protein; Medicine; Bone marrow; Differentiation therapy; Cell growth; Cell cycle; Progenitor cell; Leukemia; Immunology; Stem cell; Apoptosis; Biology; Cell culture; Annexin; Internal medicine; Cancer; Cell biology; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000327473,0.0002017575,0.0002316845,0.00004180792,0.00007819664,0.00004357411,0.0002498384,0.0002862188,0.00004267679],"category_scores_gemma":[0.0001563865,0.0001796679,0.00008595702,0.0001054647,0.0002435043,0.000006386599,0.0002575519,0.0001771773,0.00002496086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002135474,"about_ca_system_score_gemma":0.0003677408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002142316,"about_ca_topic_score_gemma":0.000006043766,"domain_scores_codex":[0.9983046,0.00007968074,0.0004244149,0.0006620146,0.0001739386,0.0003553222],"domain_scores_gemma":[0.9991446,0.00001317718,0.0001189559,0.0005018294,0.0001066595,0.0001148134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003030806,0.0002609334,0.01721238,0.00009302495,0.0001976572,0.0001862189,0.0002550622,0.000005643194,0.977943,0.00005735424,0.001512357,0.001973278],"study_design_scores_gemma":[0.002906829,0.001077057,0.002552226,0.00005377122,0.00009143588,0.0002122296,0.00006526398,0.0001818569,0.9759498,0.0006897575,0.01584486,0.0003748632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995647,0.001031084,0.0005107502,0.0002097969,0.0001384955,0.0002411423,0.00001678693,0.000018638,0.002186349],"genre_scores_gemma":[0.9929588,0.0006710011,0.003634131,0.0003697578,0.0005018464,0.00003493036,0.00004839381,0.00003063004,0.001750514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01466016,"threshold_uncertainty_score":0.7326644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007066961688592632,"score_gpt":0.2533104579737238,"score_spread":0.2462434962851312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}