{"id":"W2913552625","doi":"10.1038/s41379-019-0204-1","title":"Ductal carcinoma in situ of the breast: an update for the pathologist in the era of individualized risk assessment and tailored therapies","year":2019,"lang":"en","type":"review","venue":"Modern Pathology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Ductal carcinoma; Pathology; Carcinoma in situ; In situ; Carcinoma; Breast cancer; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007726451,0.0003523645,0.0009960197,0.00005368081,0.00008396621,0.00001290803,0.0006282171,0.0003094564,0.000001806002],"category_scores_gemma":[0.00003917735,0.0001648203,0.0002667703,0.0001156331,0.0005399267,0.00000505624,0.0003261631,0.0003325605,2.777404e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003056462,"about_ca_system_score_gemma":0.0001861731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001152434,"about_ca_topic_score_gemma":0.0006099598,"domain_scores_codex":[0.9975044,0.001066235,0.0005120158,0.0005151454,0.0001326414,0.000269634],"domain_scores_gemma":[0.9982533,0.000194878,0.0005692952,0.0009088726,0.00005930082,0.00001439291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0003336197,0.00076194,0.09055246,0.002418702,0.0007905931,0.00003456353,0.005159365,0.00004652044,0.0009266976,0.0003772805,0.00008463809,0.8985136],"study_design_scores_gemma":[0.007758613,0.001550956,0.944961,0.001356926,0.003714181,0.001926906,0.002265552,0.0001138117,0.0002478744,0.00317518,0.03175396,0.001175071],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1955985,0.8014592,0.0001350571,0.000301752,0.0001208569,0.0014433,0.0009117562,0.000002600724,0.00002702643],"genre_scores_gemma":[0.4901919,0.5089967,0.0001527742,0.00005846119,0.00003753659,0.0003823683,0.0001545914,0.00002224953,0.000003449299],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8973386,"threshold_uncertainty_score":0.6721177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03537480353786879,"score_gpt":0.3383022944487991,"score_spread":0.3029274909109303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}