{"id":"W2913648166","doi":"10.1182/blood-2018-99-110051","title":"Padi4 Regulates NET Formation and Inflammatory Cell Death Downstream of Mlkl","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Necroptosis; Cell biology; Programmed cell death; Biology; Neutrophil extracellular traps; Apoptosis; Biochemistry; Inflammation; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001500444,0.0003257935,0.0002058876,0.0002794839,0.0002532701,0.0004963741,0.0003578849,0.0003164134,0.002016783],"category_scores_gemma":[0.0001302798,0.0001678024,0.0002676469,0.000148243,0.0003633039,0.0002357662,0.0003088226,0.0008150866,0.0006188249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008416197,"about_ca_system_score_gemma":0.0002829946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004071582,"about_ca_topic_score_gemma":0.0005220984,"domain_scores_codex":[0.9998003,0.00002770478,0.00001475596,0.00005120904,0.00004113036,0.0000648835],"domain_scores_gemma":[0.999841,0.00001326286,0.00006129497,0.00001358757,0.00001605166,0.00005482569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002602322,0.00004177824,0.0004680927,0.00004179015,0.000004960255,0.00005968304,0.00001024228,0.00009610878,0.9980762,0.0001918177,0.00007905481,0.000669949],"study_design_scores_gemma":[0.00004641998,0.0002212361,0.01354207,0.000008476318,0.00001639984,0.0003147094,0.00006369382,0.002126134,0.9813504,0.0001191686,0.002186188,0.000005075042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904185,0.001631857,0.004213296,0.0002219984,0.00003730618,0.000039028,0.0009717117,0.0001988953,0.002267318],"genre_scores_gemma":[0.9942394,0.0003383505,0.001649858,0.00007392428,0.000006452493,0.00005961792,0.000913762,0.00002901027,0.002689691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002016783,"threshold_uncertainty_score":0.006746829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00834533197737533,"score_gpt":0.1988019909257967,"score_spread":0.1904566589484214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}