{"id":"W2913653887","doi":"10.1021/acs.orglett.8b04093","title":"A Route to Polyprenol Pyrophosphate-Based Probes of <i>O</i>-Polysaccharide Biosynthesis in <i>Klebsiella pneumoniae</i> O2a","year":2019,"lang":"en","type":"article","venue":"Organic Letters","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Canadian Glycomics Network; Natural Sciences and Engineering Research Council of Canada; Alberta Glycomics Centre","keywords":"Chemistry; Glycan; Biosynthesis; Polysaccharide; Klebsiella pneumoniae; Pyrophosphate; Isocoumarin; Moiety; Stereochemistry; Biochemistry; Glycosylation; Gene; Escherichia coli; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001467948,0.0005708555,0.0002001323,0.0001618727,0.0002552594,0.0003708528,0.0003069174,0.0004223818,0.0008577442],"category_scores_gemma":[0.0001338604,0.0002426683,0.0002231051,0.0001437534,0.0001976351,0.0002751377,0.0003722936,0.000952067,0.0006690469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002993545,"about_ca_system_score_gemma":0.000329913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007274949,"about_ca_topic_score_gemma":0.001149953,"domain_scores_codex":[0.9998598,0.00002566907,0.000006939534,0.00003289486,0.00003968241,0.00003499469],"domain_scores_gemma":[0.9999096,0.00001085954,0.00002555876,0.00001295241,0.00001891452,0.00002213119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005531459,0.00001727747,0.00004684658,0.00003604507,0.000003653807,0.00006508508,0.00003418148,0.000185598,0.996114,0.0007750107,0.0001035078,0.002563411],"study_design_scores_gemma":[0.00001391509,0.0001980486,0.0003037732,0.000004761217,0.000005653842,0.0001934348,0.00001612253,0.0003512815,0.9910043,0.0001589524,0.007738474,0.0000111815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7648858,0.005959129,0.1974256,0.0006674904,0.0003154502,0.0003863251,0.002002401,0.0007719909,0.02758578],"genre_scores_gemma":[0.9300655,0.003353201,0.05776516,0.0002140974,0.0000354173,0.0001637002,0.0008666125,0.0001413675,0.007394987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008577442,"threshold_uncertainty_score":0.002869427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004960523691679868,"score_gpt":0.1840093693713342,"score_spread":0.1790488456796543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}