{"id":"W2913710712","doi":"10.1002/chin.200208094","title":"ChemInform Abstract: Design and Synthesis of a Novel Class of Histone Deacetylase Inhibitors.","year":2002,"lang":"en","type":"article","venue":"ChemInform","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Association of Nurses in Oncology","funders":"","keywords":"Chemistry; Histone deacetylase; Class (philosophy); Combinatorial chemistry; Histone; Nanotechnology; Computational biology; Biochemistry; Artificial intelligence; Computer science; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003027104,0.001225015,0.0006474248,0.0005426652,0.0003418969,0.0006470066,0.0008352957,0.0004751049,0.009231351],"category_scores_gemma":[0.0001790133,0.0004384429,0.0005056098,0.0004962518,0.0002265119,0.0005559725,0.0003808382,0.000972903,0.005530274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006995311,"about_ca_system_score_gemma":0.001070604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001071772,"about_ca_topic_score_gemma":0.002868371,"domain_scores_codex":[0.9998538,0.00001262027,0.00001136369,0.00003226691,0.00005404372,0.00003595428],"domain_scores_gemma":[0.9999329,0.000003589471,0.00001096045,0.00000455231,0.00001238106,0.00003558908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001476869,0.0007811903,0.0002707865,0.001854137,0.000193912,0.0005197595,0.0001200519,0.003960413,0.7479911,0.008965296,0.04720093,0.1866654],"study_design_scores_gemma":[0.001019284,0.002260227,0.0007215276,0.00009365223,0.0001965256,0.0007539093,0.00002414975,0.003096111,0.7047097,0.001011374,0.2860302,0.00008332144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.3153472,0.1174785,0.2930431,0.005667115,0.006837963,0.005142024,0.02218373,0.01057623,0.2237243],"genre_scores_gemma":[0.6145989,0.09918068,0.1168848,0.003046776,0.0007383159,0.001372664,0.01947918,0.0007070593,0.1439915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009231351,"threshold_uncertainty_score":0.030882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02361473925936777,"score_gpt":0.2757066543123259,"score_spread":0.2520919150529581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}