{"id":"W2913734302","doi":"10.1084/jem.20180871","title":"Antigen-presenting ILC3 regulate T cell–dependent IgA responses to colonic mucosal bacteria","year":2019,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":148,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Center for Innovative Medicine; Biotechnology and Biological Sciences Research Council; CH.I.L.D. Foundation; Medical Research Council; Directorate for Biological Sciences; Royal Society; University of Liverpool; Lister Institute of Preventive Medicine; University of Manchester; Wellcome Trust; Åke Wiberg Stiftelse","keywords":"Immunology; Immune system; Biology; Innate lymphoid cell; Immunoglobulin A; Antigen presentation; Mesenteric lymph nodes; Antigen; Mucosal immunology; Intestinal mucosa; Lymphatic system; T cell; Immunity; Medicine; Immunoglobulin G; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001543806,0.0003239441,0.0001533877,0.0001824078,0.0002716626,0.000337882,0.0001389167,0.0003485197,0.001391453],"category_scores_gemma":[0.0002055606,0.0001035423,0.000204292,0.0001186216,0.0002984591,0.0001957523,0.0002493281,0.0007703695,0.0003419176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004948855,"about_ca_system_score_gemma":0.000512571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001586121,"about_ca_topic_score_gemma":0.003022762,"domain_scores_codex":[0.9998602,0.00002817216,0.00000639044,0.00001603546,0.00002192345,0.00006729273],"domain_scores_gemma":[0.9998191,0.00002467476,0.00003641422,0.00001564676,0.00004232095,0.00006185607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004965679,0.00003325648,0.0008256814,0.0000278308,0.000002550715,0.00007909882,0.00005656778,0.0001154355,0.9961758,0.0001332021,0.0001238253,0.001930166],"study_design_scores_gemma":[0.0002383304,0.0006560956,0.06176493,0.00004245893,0.00004169393,0.0003757574,0.0003782709,0.005705462,0.9245697,0.0005961173,0.005608694,0.00002256496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953142,0.0010992,0.001520321,0.0001789543,0.00002886409,0.00003085993,0.0001579739,0.00008428741,0.001585255],"genre_scores_gemma":[0.9979091,0.0002435242,0.0007153145,0.00008626839,0.00001019541,0.00003412529,0.0001101208,0.0000172021,0.0008740962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001586121,"threshold_uncertainty_score":0.004654825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01679627819688619,"score_gpt":0.2780525812223674,"score_spread":0.2612563030254812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}