{"id":"W2913734302","doi":"10.1084/jem.20180871","title":"Antigen-presenting ILC3 regulate T cell–dependent IgA responses to colonic mucosal bacteria","year":2019,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":148,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Center for Innovative Medicine; Biotechnology and Biological Sciences Research Council; CH.I.L.D. Foundation; Medical Research Council; Directorate for Biological Sciences; Royal Society; University of Liverpool; Lister Institute of Preventive Medicine; University of Manchester; Wellcome Trust; Åke Wiberg Stiftelse","keywords":"Immunology; Immune system; Biology; Innate lymphoid cell; Immunoglobulin A; Antigen presentation; Mesenteric lymph nodes; Antigen; Mucosal immunology; Intestinal mucosa; Lymphatic system; T cell; Immunity; Medicine; Immunoglobulin G; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001127959,0.0002156149,0.0004748579,0.0001694385,0.0001930217,0.00001082091,0.0005148881,0.0001205073,0.001366542],"category_scores_gemma":[0.0001214772,0.000130085,0.00008709427,0.0001491725,0.0002563012,0.0001203807,0.0001858303,0.0003880748,0.0005303964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008238972,"about_ca_system_score_gemma":0.0001040726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000626425,"about_ca_topic_score_gemma":0.000003359561,"domain_scores_codex":[0.9981961,0.000468371,0.0006087865,0.0001667045,0.0001530145,0.0004069689],"domain_scores_gemma":[0.9987985,0.0002606908,0.0004024179,0.0003485227,0.0001167765,0.00007308678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002068136,0.000123489,0.001033274,0.000009609141,0.0001032059,0.00003005505,0.00636255,0.000002899087,0.9845086,0.00006078459,0.005612211,0.00008512714],"study_design_scores_gemma":[0.003017243,0.002341687,0.00700107,0.0001566265,0.00004290915,0.0008615803,0.005959539,0.000001196858,0.9462137,0.00002392025,0.03422842,0.0001520707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879396,0.005519065,0.00001777236,0.0007156505,0.00333802,0.0002909436,0.00003833081,0.00001748623,0.002123148],"genre_scores_gemma":[0.9941465,0.0002842684,0.00005513641,0.0004929073,0.0003030574,0.000002548692,0.000009213595,0.00002400151,0.004682397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03829492,"threshold_uncertainty_score":0.9995463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01679627819688619,"score_gpt":0.2780525812223674,"score_spread":0.2612563030254812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}