{"id":"W2913747273","doi":"10.1016/j.ijdevneu.2019.01.005","title":"Surface‐ and voxel‐based brain morphologic study in Rett and Rett‐like syndrome with <i>MECP2</i> mutation","year":2019,"lang":"en","type":"article","venue":"International Journal of Developmental Neuroscience","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Francis Xavier University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Rett syndrome; MECP2; Gyrification; Cerebellum; Microcephaly; Neurodevelopmental disorder; Neuroscience; Voxel-based morphometry; Psychology; Cerebral cortex; Biology; White matter; Medicine; Pathology; Autism; Magnetic resonance imaging; Genetics; Phenotype; Developmental psychology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001988279,0.0003219512,0.0002284195,0.0007154315,0.0001184736,0.0002506172,0.0001746507,0.0002601068,0.0008234061],"category_scores_gemma":[0.0006978535,0.000234642,0.0002383964,0.0003094908,0.0003852296,0.0002193427,0.0002631063,0.0001823723,0.0001462419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001603595,"about_ca_system_score_gemma":0.0001445907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002146634,"about_ca_topic_score_gemma":0.002340533,"domain_scores_codex":[0.999887,0.00001836279,0.00001181083,0.00003742759,0.00002771429,0.00001759943],"domain_scores_gemma":[0.9997454,0.000055828,0.00009429448,0.00002143533,0.00004129081,0.00004176638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001026912,0.00009973974,0.6503655,0.00008522387,0.0002998161,0.01407829,0.001235845,0.001398837,0.3149185,0.0002245523,0.0002911389,0.01597577],"study_design_scores_gemma":[0.00001359649,0.0002021806,0.9729129,0.000004037279,0.00004218898,0.01927867,0.0002174862,0.001001507,0.006104923,0.00006385484,0.0001488815,0.000009662897],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996202,0.00002810489,0.0001928599,0.000004793337,5.782604e-7,0.000001792424,0.0000525761,0.00000870516,0.00009030435],"genre_scores_gemma":[0.9990853,0.00003103294,0.000639991,0.000007316545,0.000001795601,0.000004412313,0.0001290964,0.000009854344,0.00009120687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002146634,"threshold_uncertainty_score":0.004268348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01035248171956152,"score_gpt":0.2461635158756181,"score_spread":0.2358110341560566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}