{"id":"W2913756819","doi":"10.1016/j.bbmt.2020.05.001","title":"Risk Factors for Graft-versus-Host Disease in Haploidentical Hematopoietic Cell Transplantation Using Post-Transplant Cyclophosphamide","year":2020,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Baker Hughes (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Takeda Oncology; Health Resources and Services Administration; Daiichi-Sankyo; Swedish Orphan Biovitrum; Omeros Corporation; Janssen Scientific Affairs; Mundipharma EDO; Astellas Pharma; Adaptive Biotechnologies; bluebird bio; Medical College of Wisconsin; Chimerix; Medac; Jazz Pharmaceuticals; National Institutes of Health; Regeneron Pharmaceuticals; Karyopharm Therapeutics; Janssen Pharmaceuticals; Memorial Sloan-Kettering Cancer Center; Sanofi Genzyme; Patient-Centered Outcomes Research Institute; Janssen Biotech; HistoGenetics; Celgene; Atara Biotherapeutics; Actinium Pharmaceuticals; Daiichi Sankyo Europe; National Cancer Institute; Gilead Sciences; Sanofi; Spectrum Pharmaceuticals; Biomedical Advanced Research and Development Authority; Amgen; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Incyte; Pfizer; CSL Behring; Bristol-Myers Squibb; GlaxoSmithKline; Astellas Pharma US","keywords":"Medicine; Hazard ratio; Internal medicine; Graft-versus-host disease; Myeloid leukemia; Transplantation; Cyclophosphamide; Gastroenterology; Hematopoietic stem cell transplantation; Incidence (geometry); Bone marrow; Leukemia; Immunology; Surgery; Confidence interval; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003892942,0.0001533224,0.0002192733,0.0003713095,0.0001836204,0.000355277,0.0002341088,0.0002855463,0.001114087],"category_scores_gemma":[0.001481246,0.0001488061,0.0003683336,0.0007152294,0.000189466,0.0002385055,0.0002644722,0.0005278011,0.0001034123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001947983,"about_ca_system_score_gemma":0.0003501425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002039136,"about_ca_topic_score_gemma":0.002746223,"domain_scores_codex":[0.9997441,0.00007105002,0.0000321295,0.00004654498,0.00005883427,0.00004728467],"domain_scores_gemma":[0.9990251,0.0002060542,0.0005108857,0.00004136996,0.00003561868,0.0001809385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001085897,0.00002256413,0.9983,0.000004524516,0.00002301625,0.00008974204,0.00001912561,0.00006434195,0.0002170903,0.00001521077,0.00005201827,0.001083795],"study_design_scores_gemma":[0.000009093002,0.0000918294,0.9989268,0.00000758539,0.00002535579,0.0003682813,0.00004864514,0.0002623101,0.00008735681,0.0000192914,0.0001509495,0.000002364814],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999315,0.0003494447,0.00004898275,0.00003904627,0.000004072321,0.000003711527,0.00006325814,0.000001883185,0.0001746132],"genre_scores_gemma":[0.9997632,0.00008190703,0.00002819746,0.00001471202,0.000007378503,0.000002315081,0.00006563631,8.18092e-7,0.00003586428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002039136,"threshold_uncertainty_score":0.004054546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02030487521731368,"score_gpt":0.2621069434480915,"score_spread":0.2418020682307778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}