{"id":"W2913756819","doi":"10.1016/j.bbmt.2020.05.001","title":"Risk Factors for Graft-versus-Host Disease in Haploidentical Hematopoietic Cell Transplantation Using Post-Transplant Cyclophosphamide","year":2020,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Baker Hughes (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Takeda Oncology; Health Resources and Services Administration; Daiichi-Sankyo; Swedish Orphan Biovitrum; Omeros Corporation; Janssen Scientific Affairs; Mundipharma EDO; Astellas Pharma; Adaptive Biotechnologies; bluebird bio; Medical College of Wisconsin; Chimerix; Medac; Jazz Pharmaceuticals; National Institutes of Health; Regeneron Pharmaceuticals; Karyopharm Therapeutics; Janssen Pharmaceuticals; Memorial Sloan-Kettering Cancer Center; Sanofi Genzyme; Patient-Centered Outcomes Research Institute; Janssen Biotech; HistoGenetics; Celgene; Atara Biotherapeutics; Actinium Pharmaceuticals; Daiichi Sankyo Europe; National Cancer Institute; Gilead Sciences; Sanofi; Spectrum Pharmaceuticals; Biomedical Advanced Research and Development Authority; Amgen; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Incyte; Pfizer; CSL Behring; Bristol-Myers Squibb; GlaxoSmithKline; Astellas Pharma US","keywords":"Medicine; Hazard ratio; Internal medicine; Graft-versus-host disease; Myeloid leukemia; Transplantation; Cyclophosphamide; Gastroenterology; Hematopoietic stem cell transplantation; Incidence (geometry); Bone marrow; Leukemia; Immunology; Surgery; Confidence interval; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002016518,0.0003281747,0.0005763934,0.0001914894,0.00009501931,0.00001269279,0.00009319127,0.0002434431,0.00002403972],"category_scores_gemma":[0.00004941769,0.0003091475,0.0001851186,0.0002090752,0.0001727577,0.0001500777,0.000004164334,0.0002018687,0.000001966107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001608172,"about_ca_system_score_gemma":0.000119696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003547133,"about_ca_topic_score_gemma":0.00009695635,"domain_scores_codex":[0.9980122,0.0001275624,0.0007392145,0.0005461897,0.0002042403,0.0003705812],"domain_scores_gemma":[0.9986673,0.000560287,0.0002002002,0.0001357883,0.00009767064,0.0003387471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00916211,0.0002739252,0.4617162,0.005786886,0.0001399385,0.0001267029,0.006559214,0.00008684635,0.5156716,0.0004071572,0.000001322237,0.00006809957],"study_design_scores_gemma":[0.02908772,0.00241655,0.4752509,0.001039698,0.009587825,0.0001661208,0.001134062,0.00163261,0.4784843,0.0003029076,0.00002155631,0.0008756929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788284,0.0006076433,0.017045,0.000319933,0.0001550934,0.001149897,0.001791141,0.00006215976,0.00004072494],"genre_scores_gemma":[0.9915356,0.003756932,0.002570282,0.0001049487,0.00005017404,0.00003797633,0.001899161,0.00004118659,0.00000373272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03718726,"threshold_uncertainty_score":0.999936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02030487521731368,"score_gpt":0.2621069434480915,"score_spread":0.2418020682307778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}