{"id":"W2913788535","doi":"10.2147/ott.s191478","title":"<p>Potent in vitro and xenograft antitumor activity of a novel agent, PV-10, against relapsed and refractory neuroblastoma</p>","year":2019,"lang":"en","type":"article","venue":"OncoTargets and Therapy","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital","funders":"National Cancer Institute","keywords":"Neuroblastoma; Flow cytometry; In vitro; In vivo; Cancer research; Medicine; Cell culture; Cytotoxicity; Cytotoxic T cell; In vitro toxicology; Cancer; Pharmacology; Immunology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001855073,0.0003697627,0.0003034967,0.0002249843,0.0000950204,0.0001695995,0.0003314331,0.0002045802,0.0009484812],"category_scores_gemma":[0.00008942102,0.0001126303,0.0001875431,0.0001525167,0.0002007837,0.0001865816,0.0001066804,0.0005905528,0.0003462772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003120441,"about_ca_system_score_gemma":0.0003874264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001920233,"about_ca_topic_score_gemma":0.00340839,"domain_scores_codex":[0.999912,0.00001822517,0.000007712132,0.00001681661,0.00002416517,0.00002092671],"domain_scores_gemma":[0.9999244,0.00001676669,0.00001706968,0.00001108615,0.000008531945,0.00002211495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004648295,0.0004203921,0.000306986,0.0001471023,0.00001674278,0.0002299949,0.00003167461,0.0008892611,0.9893886,0.0001195936,0.0004725153,0.00751223],"study_design_scores_gemma":[0.0002393579,0.007426101,0.004143776,0.000022046,0.00004590437,0.0007556905,0.00002314159,0.002817324,0.9802081,0.00004447405,0.004264455,0.000009663294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918476,0.002193289,0.001463103,0.0001260046,0.00006510646,0.0000762185,0.0005583108,0.0001411998,0.0035292],"genre_scores_gemma":[0.9914766,0.001566514,0.002539205,0.00005913097,0.00001525862,0.00006857232,0.00101083,0.00002240778,0.003241403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001920233,"threshold_uncertainty_score":0.003818095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01872623982596687,"score_gpt":0.2721011470440515,"score_spread":0.2533749072180846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}