{"id":"W2913788535","doi":"10.2147/ott.s191478","title":"<p>Potent in vitro and xenograft antitumor activity of a novel agent, PV-10, against relapsed and refractory neuroblastoma</p>","year":2019,"lang":"en","type":"article","venue":"OncoTargets and Therapy","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital","funders":"National Cancer Institute","keywords":"Neuroblastoma; Flow cytometry; In vitro; In vivo; Cancer research; Medicine; Cell culture; Cytotoxicity; Cytotoxic T cell; In vitro toxicology; Cancer; Pharmacology; Immunology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002038162,0.0002940301,0.0005841634,0.000250177,0.00007528457,0.00003260455,0.00006952664,0.0001006362,0.00004158998],"category_scores_gemma":[0.0000390225,0.0002277186,0.00007955065,0.0001892096,0.0001795123,0.0001808172,0.00008248643,0.0002541123,0.000008107231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004190773,"about_ca_system_score_gemma":0.00008330269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003470507,"about_ca_topic_score_gemma":0.00002484281,"domain_scores_codex":[0.9983448,0.00008561342,0.0002680678,0.0005338678,0.0003405673,0.0004270227],"domain_scores_gemma":[0.9990236,0.0001457118,0.000137307,0.0003310455,0.00006537289,0.0002969774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004142701,0.001463867,0.006393843,0.0001192183,0.0001266097,0.0002309675,0.0001871104,0.000001415398,0.9596413,0.00002603353,0.0001153452,0.02755155],"study_design_scores_gemma":[0.04102711,0.008495127,0.7085723,0.0003957346,0.00006217128,0.0002413066,0.00003875008,0.001867767,0.1902166,0.0000522851,0.04843513,0.0005957714],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947792,0.002590146,0.000006525129,0.0004684913,0.00009134917,0.0007649943,0.00004637353,0.00003056109,0.001222409],"genre_scores_gemma":[0.9902539,0.008243359,0.000237539,0.0002524086,0.00003715351,0.00001911114,0.00001593252,0.00004346548,0.0008971557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7694247,"threshold_uncertainty_score":0.9286094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01872623982596687,"score_gpt":0.2721011470440515,"score_spread":0.2533749072180846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}