{"id":"W2913792143","doi":"10.1073/pnas.1821197116","title":"CD4 receptor diversity in chimpanzees protects against SIV infection","year":2019,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Fonds de Recherche du Québec - Santé; Tanzania Wildlife Research Institute; Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs; Yerkes National Primate Research Center, Emory University; Government of Canada; Tanzania Commission for Science and Technology; Styrelsen för Internationellt Utvecklingssamarbete; World Wildlife Fund","keywords":"Biology; Simian immunodeficiency virus; Virology; Genetics; Simian; Lentivirus; Allele; Virus; Gene; Viral disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001600001,0.0002947766,0.0002369003,0.0003425339,0.000284813,0.0003303898,0.0001456963,0.0002124852,0.001743169],"category_scores_gemma":[0.000313096,0.0002530738,0.0001392758,0.0001233075,0.0003624949,0.0001368093,0.0002673765,0.0004767846,0.0001374315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573984,"about_ca_system_score_gemma":0.00009976236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001346987,"about_ca_topic_score_gemma":0.001496686,"domain_scores_codex":[0.9999008,0.00002755394,0.00000557928,0.00003168477,0.00001344207,0.0000208478],"domain_scores_gemma":[0.999896,0.00001655149,0.00002187207,0.00001330602,0.000005818238,0.00004644062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001213721,0.0001300467,0.03421815,0.0000858955,0.0001290583,0.0006902842,0.0002942697,0.0002262736,0.9551153,0.0002932902,0.0001356304,0.007468141],"study_design_scores_gemma":[0.0003230067,0.004467455,0.8983485,0.0000488689,0.0002770181,0.007845803,0.00115529,0.001823065,0.07721349,0.0008317508,0.007596817,0.00006891436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994072,0.0002246411,0.00008351504,0.00002175728,0.000003103212,0.000002617536,0.0000276629,0.000009695988,0.0002197736],"genre_scores_gemma":[0.9993241,0.0001337425,0.0001898952,0.00002725312,0.00000361314,0.000005186053,0.00005445129,0.000006052873,0.0002557676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001743169,"threshold_uncertainty_score":0.00583148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03706474773112494,"score_gpt":0.2924138693912648,"score_spread":0.2553491216601398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}