{"id":"W2913819594","doi":"10.1016/j.jacc.2018.11.042","title":"Effects of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in Patients With HFrEF","year":2019,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":249,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Sacubitril, Valsartan; Medicine; Valsartan; Extracellular matrix; Sacubitril; Internal medicine; Cardiology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004523718,0.0001538846,0.001332785,0.0002906409,0.00002683605,7.567982e-7,0.0003101241,0.0001233257,0.00000901246],"category_scores_gemma":[0.0001581514,0.00009734472,0.0002608747,0.0004230365,0.0005389435,0.00005038951,0.00004752184,0.0002352696,0.000004439664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005684287,"about_ca_system_score_gemma":0.000155454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001955091,"about_ca_topic_score_gemma":0.000002287416,"domain_scores_codex":[0.9981335,0.0007373153,0.0006669765,0.0001384842,0.000113903,0.000209853],"domain_scores_gemma":[0.997246,0.0004293981,0.001730746,0.0003085228,0.0002679589,0.00001733242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.007440346,0.0002093747,0.3256206,0.0001407124,0.0009838657,0.00001366432,0.00009817837,0.0007702087,0.6628519,0.0005414807,0.0009299986,0.000399677],"study_design_scores_gemma":[0.005601982,0.006029068,0.7925821,0.0002833964,0.0002256431,0.00008481936,0.0002547953,0.000002945341,0.1915305,0.0001175894,0.003135347,0.0001518494],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977179,0.0006865843,0.00005823482,0.00004055015,0.0005000737,0.0003461753,0.0002641405,0.000002450284,0.0003839434],"genre_scores_gemma":[0.9995841,0.00004874838,0.0001084487,0.00001459313,0.00002172918,0.000001517632,0.00000477383,0.00001358192,0.0002024656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4713215,"threshold_uncertainty_score":0.3969603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002887529432387205,"score_gpt":0.1951125964249943,"score_spread":0.1922250669926071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}