{"id":"W2913876654","doi":"10.1177/1179069519825882","title":"Unexpected Microglial “De-activation” Associated With Altered Synaptic Transmission in the Early Stages of an Animal Model of Multiple Sclerosis","year":2019,"lang":"en","type":"article","venue":"Journal of Experimental Neuroscience","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Neuroscience; Multiple sclerosis; Microglia; Medicine; Neurotransmission; Biology; Psychology; Inflammation; Psychiatry; Immunology; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003451436,0.0001421082,0.0002351283,0.0002036134,0.0000861755,0.00005675016,0.0005182738,0.0000398592,0.00001509217],"category_scores_gemma":[0.0002514447,0.00009986059,0.00007151959,0.0004968829,0.0001554773,0.0008019,0.00002643677,0.000211497,4.459519e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003804967,"about_ca_system_score_gemma":0.0001155306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006414398,"about_ca_topic_score_gemma":9.817043e-7,"domain_scores_codex":[0.9978405,0.0003937128,0.0005598278,0.0002610242,0.0007415569,0.0002033441],"domain_scores_gemma":[0.9987829,0.0001985439,0.0006643648,0.0001906131,0.00008335957,0.00008015797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003944327,0.0005238537,0.0005380925,0.000004634175,0.00000114279,0.000008567819,0.00152261,0.00653958,0.9902841,0.0001528383,0.000002890826,0.00002723566],"study_design_scores_gemma":[0.001268431,0.002233883,0.005162409,0.00005752444,0.000004422916,0.00003454087,0.0002051779,0.05794038,0.9329903,0.00001350038,0.000001533315,0.00008791399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986939,0.000006469313,0.0007590267,0.0001170463,0.000104695,0.0002704981,0.00001188839,0.00001063915,0.00002577298],"genre_scores_gemma":[0.9991066,0.000008279406,0.0004831855,0.0003408613,0.00001265679,0.000003520487,4.135932e-7,0.00001474275,0.00002974495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05729384,"threshold_uncertainty_score":0.4072196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06219325012338094,"score_gpt":0.2716235076612712,"score_spread":0.2094302575378903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}