{"id":"W2913903170","doi":"10.1093/nar/gkz099","title":"SAM68 interaction with U1A modulates U1 snRNP recruitment and regulates mTor pre-mRNA splicing","year":2019,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Centre Hospitalier Universitaire de Québec; Université Laval","keywords":"snRNP; RNA splicing; Biology; Intron; Ribonucleoprotein; Polyadenylation; RNA-binding protein; Cell biology; Genetics; Alternative splicing; Exonic splicing enhancer; SR protein; Exon; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008076482,0.0002052878,0.0001771653,0.0001191058,0.0003245184,0.0002193902,0.0001503893,0.000183666,0.001411799],"category_scores_gemma":[0.0001356973,0.0001017144,0.0001683772,0.00009181817,0.0001669373,0.0001649742,0.0002230722,0.00019762,0.0004057476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001782227,"about_ca_system_score_gemma":0.0001044852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004519941,"about_ca_topic_score_gemma":0.0007200828,"domain_scores_codex":[0.9998871,0.00002189366,0.000005548946,0.00002306656,0.00002002587,0.00004234732],"domain_scores_gemma":[0.9999462,0.000006721273,0.00001805028,0.000002767184,0.000004757826,0.0000214546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003910137,0.00002700485,0.0008620016,0.00005819351,0.000008835388,0.0001411232,0.00003467005,0.00005798179,0.9953303,0.00023986,0.0001110408,0.002738083],"study_design_scores_gemma":[0.00004407944,0.0003034551,0.02779549,0.00001517556,0.00002230714,0.0004616049,0.0001166592,0.002961538,0.9637868,0.0001668151,0.004315277,0.00001068085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960743,0.002088713,0.0007129515,0.00006391609,0.00002135601,0.000004256668,0.00004599117,0.00003458236,0.0009539022],"genre_scores_gemma":[0.9985641,0.0003922162,0.000339735,0.00002239084,0.000007304963,0.000005107361,0.00006482627,0.000005796961,0.0005985415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001411799,"threshold_uncertainty_score":0.004722953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04388633337406636,"score_gpt":0.3522749579945549,"score_spread":0.3083886246204885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}