{"id":"W2913938016","doi":"10.1002/stem.2976","title":"Human Multipotent Stromal Cell Secreted Effectors Accelerate Islet Regeneration","year":2019,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Krembil Foundation; Robarts Clinical Trials; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Juvenile Diabetes Research Foundation United States of America","keywords":"Regeneration (biology); Biology; Cell biology; Islet; Stromal cell; Stem cell; Wnt signaling pathway; Transplantation; Mesenchymal stem cell; Regenerative medicine; Immunology; Insulin; Endocrinology; Internal medicine; Signal transduction; Cancer research; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001265507,0.0003039875,0.0001660948,0.0002182587,0.00006392441,0.0001833764,0.00009195539,0.0001773284,0.002992808],"category_scores_gemma":[0.00007119768,0.00006388224,0.0002198125,0.0001099096,0.0001301415,0.00008559713,0.0001994423,0.0004849982,0.0007745044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000133802,"about_ca_system_score_gemma":0.0001177636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002043705,"about_ca_topic_score_gemma":0.0003313026,"domain_scores_codex":[0.9999039,0.00001624257,0.000008489006,0.00001507155,0.00003068783,0.00002564116],"domain_scores_gemma":[0.9999236,0.00001565195,0.00001332909,0.000008701444,0.000007625417,0.00003104906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002800741,0.00007129358,0.0002399682,0.00004249282,0.000005379836,0.00006884607,0.0000109136,0.00009217,0.9953322,0.00007711027,0.0001658076,0.00361379],"study_design_scores_gemma":[0.00003491542,0.000520368,0.002983226,0.000007281715,0.00001000882,0.0001592179,0.00001462649,0.000586988,0.9922736,0.00003841201,0.003369299,0.000002070623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915293,0.001876237,0.002646114,0.0001109577,0.00009050363,0.00005041231,0.0007145872,0.0002183815,0.002763475],"genre_scores_gemma":[0.9906914,0.0005727934,0.00260044,0.00010678,0.00003331756,0.00005436135,0.001036868,0.0000264035,0.004877646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002992808,"threshold_uncertainty_score":0.01001197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0135645819177084,"score_gpt":0.2311197774043937,"score_spread":0.2175551954866853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}