{"id":"W2913991842","doi":"10.1158/1055-9965.epi-18-0826","title":"Genetic Variation in Steroid and Xenobiotic Metabolizing Pathways and Enterolactone Excretion Before and After Flaxseed Intervention in African American and European American Women","year":2019,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Phytoestrogen effects and research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute","keywords":"Enterolactone; Excretion; Single-nucleotide polymorphism; Internal medicine; Endocrinology; Biology; Physiology; Medicine; Estrogen; Genotype; Genetics; Phytoestrogens; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004180442,0.0002572337,0.0002462568,0.0002557217,0.0003764532,0.0001776491,0.0001714937,0.0003141413,0.001579405],"category_scores_gemma":[0.0009647111,0.0001643857,0.0002558098,0.0003311454,0.0002255096,0.0001112141,0.0001273085,0.0001963567,0.0001047622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002167442,"about_ca_system_score_gemma":0.0001648407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008116229,"about_ca_topic_score_gemma":0.006552627,"domain_scores_codex":[0.9997652,0.000084089,0.00001202385,0.00008090926,0.00002393797,0.00003383173],"domain_scores_gemma":[0.9997186,0.00008424657,0.000089058,0.00003029711,0.00002185468,0.00005596783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008871544,0.000627576,0.9682521,0.00003345487,0.0003693053,0.0001947114,0.0004622905,0.0001062325,0.01447343,0.00007097284,0.0001406912,0.006397726],"study_design_scores_gemma":[0.00009652501,0.0006557378,0.9982869,0.000003922281,0.0001084283,0.00007497143,0.00009306963,0.0001297462,0.0003769687,0.00002525897,0.0001452719,0.00000312761],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997879,0.00004076628,0.00003631099,0.000009089588,0.00000140404,0.000005030814,0.00004742743,0.000001234738,0.00007083994],"genre_scores_gemma":[0.9995871,0.0000246877,0.0001031846,0.00001710336,0.000002144317,0.00001317651,0.00006577394,0.000001322743,0.0001855052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008116229,"threshold_uncertainty_score":0.01613796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01594360434407216,"score_gpt":0.3123451757427483,"score_spread":0.2964015713986761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}