{"id":"W2914057743","doi":"10.1002/chin.200814142","title":"ChemInform Abstract: Substituted Phenanthrene Imidazoles as Potent, Selective, and Orally Active mPGES‐1 Inhibitors.","year":2008,"lang":"en","type":"article","venue":"ChemInform","topic":"Organic Chemistry Cycloaddition Reactions","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Phenanthrene; Orally active; Combinatorial chemistry; Stereochemistry; Pharmacology; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001351717,0.0007892516,0.0003334463,0.0004116193,0.0001546756,0.0003795694,0.0003727229,0.0003336113,0.01301781],"category_scores_gemma":[0.00009884215,0.0002110361,0.0001608563,0.0003768608,0.0001158091,0.0004075558,0.0002392387,0.0006487976,0.005189056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002988253,"about_ca_system_score_gemma":0.0002817328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002947455,"about_ca_topic_score_gemma":0.0007784527,"domain_scores_codex":[0.9999405,0.00001098016,0.00000305013,0.000009101847,0.0000197664,0.00001651377],"domain_scores_gemma":[0.9999762,0.000002813994,0.000005892944,0.000002052861,0.000003450316,0.000009703119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004779766,0.0006159179,0.0002765839,0.001718404,0.0001015004,0.0008927765,0.00007619695,0.002232261,0.6528427,0.005595942,0.06688286,0.2639851],"study_design_scores_gemma":[0.002266743,0.006105696,0.0037446,0.0001359598,0.0002184824,0.0022553,0.00003406586,0.002594846,0.6953494,0.001498193,0.2857276,0.00006905041],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.4813714,0.2008545,0.02879463,0.005032014,0.00532909,0.0009412343,0.01567717,0.005696123,0.2563039],"genre_scores_gemma":[0.7362993,0.0904296,0.00949748,0.001165019,0.0008388508,0.0002091511,0.01007245,0.0001843616,0.1513037],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01301781,"threshold_uncertainty_score":0.04354888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030425028566065,"score_gpt":0.2214437975595697,"score_spread":0.2111395472739091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}