{"id":"W2914423557","doi":"10.14309/00000434-201710001-00607","title":"Tofacitinib for Maintenance Therapy in Patients With Active Ulcerative Colitis in the Phase 3 OCTAVE Sustain Trial: Results by Local and Central Endoscopic Assessments","year":2017,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Medicine; Tofacitinib; Ulcerative colitis; Concomitant; Placebo; Clinical endpoint; Internal medicine; Randomized controlled trial; Gastroenterology; Phases of clinical research; Clinical trial; Surgery; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001764426,0.0008980369,0.001575602,0.0002581629,0.0003211636,0.001249468,0.0005183257,0.0007264699,0.003200846],"category_scores_gemma":[0.001095566,0.0002397698,0.001275504,0.0003572341,0.0003451931,0.0006997912,0.0003439295,0.001636944,0.0004083252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004774207,"about_ca_system_score_gemma":0.000711329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005895642,"about_ca_topic_score_gemma":0.00180389,"domain_scores_codex":[0.9996186,0.0001753766,0.0000261222,0.00005727366,0.00006947344,0.00005316229],"domain_scores_gemma":[0.9993449,0.0001067734,0.0002215461,0.00005386178,0.00006995784,0.0002029271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8858739,0.007675849,0.01910325,0.001100871,0.001939294,0.00009251705,0.0001483234,0.0006586774,0.006922982,0.0001680673,0.003808742,0.07250755],"study_design_scores_gemma":[0.7192707,0.1930184,0.07517568,0.0002434163,0.002062354,0.0004711142,0.0001163122,0.002098701,0.001777565,0.0004425514,0.00526263,0.00006056449],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861882,0.007416965,0.0002940669,0.0004966061,0.00008560261,0.001110774,0.001697113,0.00008937244,0.002621301],"genre_scores_gemma":[0.9886213,0.002388098,0.0009579179,0.0007711066,0.0002231683,0.001439176,0.003977517,0.00002128976,0.001600344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003200846,"threshold_uncertainty_score":0.01070791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008019787686424142,"score_gpt":0.2902811816866341,"score_spread":0.2822613940002099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}