{"id":"W2914461762","doi":"10.1016/j.ttbdis.2019.01.006","title":"Transgenic Babesia bovis lacking 6-Cys sexual-stage genes as the foundation for non-transmissible live vaccines against bovine babesiosis","year":2019,"lang":"en","type":"article","venue":"Ticks and Tick-borne Diseases","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Australian Research Council; Global Affairs Canada; Bill and Melinda Gates Foundation","keywords":"Babesia bovis; Biology; Virology; Gene; Babesiosis; Rhipicephalus microplus; Babesia; Attenuated vaccine; Genetics; Tick; Virulence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001584578,0.0002840791,0.0002032974,0.000226369,0.0001199052,0.0002587333,0.0002600555,0.0003075979,0.001189235],"category_scores_gemma":[0.0001017637,0.000188562,0.0001988061,0.0001602412,0.0002227751,0.0001450807,0.0001791244,0.0008183678,0.0004038958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000190428,"about_ca_system_score_gemma":0.0001629592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004976362,"about_ca_topic_score_gemma":0.0005511901,"domain_scores_codex":[0.9998696,0.0000258198,0.00001784394,0.00002536898,0.00003354845,0.00002781854],"domain_scores_gemma":[0.9998394,0.00002268696,0.00005584801,0.00001412437,0.0000117053,0.00005612677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006496676,0.00002774576,0.0000872476,0.00001580441,0.000002489566,0.00001831874,0.000009212559,0.00002706387,0.9993892,0.00008365687,0.000009047124,0.0002652423],"study_design_scores_gemma":[0.00005012197,0.0005227369,0.005388664,0.00001671865,0.00004694234,0.0003229241,0.0000700646,0.00226184,0.9862421,0.0001058003,0.0049639,0.000008303093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943715,0.0003760518,0.003777143,0.0001134809,0.00004387545,0.00005046904,0.0004066581,0.0000838868,0.0007768857],"genre_scores_gemma":[0.9919484,0.000424592,0.003869687,0.00005691875,0.0000103606,0.00005064414,0.0007536545,0.00004321021,0.002842494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001189235,"threshold_uncertainty_score":0.003978372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01001757184948236,"score_gpt":0.2499053905917633,"score_spread":0.2398878187422809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}