{"id":"W2914598381","doi":"10.3899/jrheum.181054","title":"Adaptive Trial Designs in Rheumatology: Report from the OMERACT Special Interest Group","year":2019,"lang":"en","type":"review","venue":"The Journal of Rheumatology","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"Sanofi; Pfizer; Celltrion; Eli Lilly and Company","keywords":"Medicine; Rheumatology; Internal medicine; Physical therapy; Family medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.02040173,0.0007526713,0.00896297,0.0002821732,0.0001154306,0.00005378291,0.002634453,0.001148303,0.0008087485],"category_scores_gemma":[0.1595809,0.0003602424,0.001460171,0.000444652,0.0007851371,0.0001014744,0.0004832524,0.004092991,0.000198344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002476347,"about_ca_system_score_gemma":0.000983627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002187369,"about_ca_topic_score_gemma":0.0002331776,"domain_scores_codex":[0.9717244,0.01837914,0.00812912,0.0004982032,0.0006238696,0.0006452878],"domain_scores_gemma":[0.6828123,0.3069661,0.008704624,0.00120354,0.0001865005,0.0001268746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0493519,0.001533383,0.0005235945,0.00654686,0.006751033,0.001503935,0.001219832,0.000001439444,2.81107e-7,0.1130958,0.08499703,0.7344749],"study_design_scores_gemma":[0.01559668,0.001442482,0.00001407938,0.02606694,0.004339037,0.02603691,0.0003431484,0.000008349038,2.423624e-7,0.7072847,0.2182122,0.0006551413],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001781983,0.9508606,0.02037643,0.0006712683,0.0217853,0.003877374,0.0001555468,0.00003413184,0.0004574087],"genre_scores_gemma":[0.0001256619,0.9589471,0.04008731,0.00003951719,0.0005834855,0.00003905647,0.000006051611,0.0001190813,0.00005273859],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7338198,"threshold_uncertainty_score":0.999885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7486996449454308,"score_gpt":0.5732690370821051,"score_spread":0.1754306078633258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}