{"id":"W2914661361","doi":"10.1093/ibd/izz008","title":"Adalimumab Effectiveness Up to Six Years in Adalimumab-naïve Patients with Crohn’s Disease: Results of the PYRAMID Registry","year":2019,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"AbbVie","keywords":"Adalimumab; Medicine; Internal medicine; Crohn's disease; Inflammatory bowel disease; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004884968,0.0002579617,0.0008191015,0.001018223,0.0002886579,0.0007105065,0.0005376719,0.0003950195,0.0005597912],"category_scores_gemma":[0.004546908,0.0001733495,0.0009767002,0.00117805,0.0002481891,0.0008627956,0.0006452011,0.000522016,0.0002181955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006235104,"about_ca_system_score_gemma":0.0005984802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001940706,"about_ca_topic_score_gemma":0.00267375,"domain_scores_codex":[0.9974762,0.0008191741,0.0003333337,0.0003755058,0.0008235996,0.0001722915],"domain_scores_gemma":[0.9950988,0.000923295,0.00233815,0.0005251651,0.0006232755,0.0004913954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01083178,0.0004447543,0.9674454,0.00008290432,0.0004838536,0.0001268398,0.0001255279,0.0003107156,0.0004614283,0.00002742831,0.000857906,0.01880143],"study_design_scores_gemma":[0.0005704665,0.003179216,0.9945281,0.00001280159,0.0003111086,0.000186807,0.00005231586,0.0004258818,0.0001895605,0.00001573542,0.0005174762,0.00001045599],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973053,0.0006299553,0.00007973428,0.00004437123,0.000006680011,0.00003305132,0.001377304,0.00001225246,0.000511308],"genre_scores_gemma":[0.996038,0.0002160328,0.0001601379,0.00004833872,0.0000289892,0.00003740303,0.003342682,0.000003145459,0.0001252282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004884968,"threshold_uncertainty_score":0.0258345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00350021243080898,"score_gpt":0.2099334316161508,"score_spread":0.2064332191853419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}