{"id":"W2914673850","doi":"10.1016/j.devcel.2019.01.005","title":"Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract","year":2019,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Hjärt-Lungfonden; EMBO; M.S.I. Foundation; AstraZeneca","keywords":"Biology; Embryonic stem cell; Heart development; Cell biology; Population; Embryonic heart; Stem cell; LGR5; Progenitor cell; Anatomy; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001204321,0.00006627796,0.0001469824,0.0003022593,0.0001397582,0.000272619,0.0001075109,0.0001407347,0.001135061],"category_scores_gemma":[0.0001079953,0.00009252677,0.0001238555,0.0001812886,0.0001119868,0.0001159284,0.0001417278,0.0001968332,0.0003281131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009887835,"about_ca_system_score_gemma":0.00007829142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008132574,"about_ca_topic_score_gemma":0.001377936,"domain_scores_codex":[0.9999568,0.000005407194,0.000003925336,0.00001464346,0.00001000158,0.000009096224],"domain_scores_gemma":[0.9999597,0.00001663342,0.000003983894,0.000006341909,0.000005312328,0.000008066837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001361948,0.0000214932,0.004490369,0.00001712408,0.000007523876,0.0001038494,0.00008365294,0.0001109199,0.9901479,0.0002345559,0.0000570704,0.004589303],"study_design_scores_gemma":[0.00003977201,0.0003220564,0.1657405,0.00001117999,0.00006874865,0.001774341,0.0003392284,0.004595844,0.8222097,0.0003382591,0.004549697,0.00001068284],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924895,0.0006995805,0.004696648,0.00002783556,0.000005584746,0.00001898869,0.0003757476,0.00002504782,0.001661204],"genre_scores_gemma":[0.9947184,0.0003043042,0.002545679,0.00002977028,0.000006541709,0.00002686629,0.0006136422,0.00001834241,0.001736463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001135061,"threshold_uncertainty_score":0.003797114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01064432567310219,"score_gpt":0.2502652961445965,"score_spread":0.2396209704714943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}