{"id":"W2914720861","doi":"10.1016/j.colsurfb.2019.02.011","title":"One-step preparation of gold nanovectors using folate modified polyethylenimine and their use in target-specific gene transfection","year":2019,"lang":"en","type":"article","venue":"Colloids and Surfaces B Biointerfaces","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Priority Academic Program Development of Jiangsu Higher Education Institutions; National Natural Science Foundation of China","keywords":"Polyethylenimine; Transfection; HeLa; Cytotoxicity; Gene delivery; Folate receptor; Molecular biology; Genetic enhancement; Cancer cell; Chemistry; Cell culture; Biology; Cell biology; Cancer research; Cell; In vitro; Cancer; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001508654,0.0001829426,0.0002632934,0.00008907607,0.00003273286,0.00005207928,0.00007999683,0.0001524805,0.000008227858],"category_scores_gemma":[0.000008459302,0.0001632964,0.00005467725,0.000102211,0.0000757123,0.00003329543,0.00005482083,0.00006341138,9.657656e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000146237,"about_ca_system_score_gemma":0.00002378471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003745159,"about_ca_topic_score_gemma":0.0003620711,"domain_scores_codex":[0.9990106,0.00006177244,0.0002883742,0.0003895209,0.00007034112,0.0001793487],"domain_scores_gemma":[0.9995814,0.00002058914,0.0001082465,0.0001840759,0.00006104332,0.00004463849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004596697,0.00004883142,0.0202911,0.00003741879,0.0000490501,2.232947e-7,0.0003597044,0.001132397,0.9769896,0.000006761129,0.00001573179,0.0006094922],"study_design_scores_gemma":[0.000707087,0.0009504342,0.00715201,0.00007079377,0.000009738913,0.000005144,0.000355886,0.007542082,0.9827066,0.00001980753,0.0002737286,0.0002067019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932461,0.005013883,0.001125313,0.0000128975,0.0001563809,0.0003146077,0.00004759637,0.000007439785,0.00007576828],"genre_scores_gemma":[0.9970604,0.00178397,0.0007514278,0.00001454337,0.0000201697,0.000004127554,0.00002563644,0.00001544194,0.0003243066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01313909,"threshold_uncertainty_score":0.6659034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0229610909128689,"score_gpt":0.2435879400254999,"score_spread":0.220626849112631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}