{"id":"W2914727986","doi":"10.3390/v11020122","title":"Back to the Future for Influenza Preimmunity—Looking Back at Influenza Virus History to Infer the Outcome of Future Infections","year":2019,"lang":"en","type":"review","venue":"Viruses","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"Office of Extramural Research, National Institutes of Health; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Nova Scotia Health Research Foundation","keywords":"Virus; Original antigenic sin; Virology; Antigenic drift; Biology; Antigenic shift; Immune system; Pandemic; Vaccination; Influenza A virus; Immunology; Infectious disease (medical specialty); Medicine; Disease; Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006948943,0.0006098961,0.001102034,0.002437892,0.0003267967,0.001321263,0.0006645224,0.001188526,0.00379681],"category_scores_gemma":[0.002298094,0.0002134123,0.0007630316,0.001883551,0.0008644578,0.003011816,0.000579414,0.00246163,0.001467415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009680617,"about_ca_system_score_gemma":0.001560784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002041979,"about_ca_topic_score_gemma":0.0022831,"domain_scores_codex":[0.9997278,0.00008820403,0.00003974298,0.00005054356,0.00007376255,0.00002003555],"domain_scores_gemma":[0.9990828,0.0006295218,0.00007685902,0.00002621649,0.0001527674,0.00003188263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001361484,0.00005245448,0.0005716048,0.03730226,0.0002873691,0.0002253414,0.0003132216,0.0005651577,0.001577794,0.02555506,0.04697556,0.886438],"study_design_scores_gemma":[0.000008697918,0.00006890203,0.001348074,0.01619119,0.0002101012,0.0009453562,0.0002325027,0.0001265643,0.0003541321,0.01322078,0.9672673,0.00002642732],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008338229,0.9980336,0.0001291153,0.0007103203,0.0003110972,0.000002042871,0.00001643552,0.000004696662,0.0007093421],"genre_scores_gemma":[0.00100844,0.9977129,0.0001628577,0.0004112514,0.0002863934,0.000003708794,0.0000229662,0.000001790718,0.0003897066],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00379681,"threshold_uncertainty_score":0.01270163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2891383036429608,"score_gpt":0.4613183593477165,"score_spread":0.1721800557047558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}