{"id":"W2914733444","doi":"10.1139/bcb-2018-0313","title":"The long noncoding RNA HOTTIP promotes breast cancer cell migration, invasiveness, and epithelial–mesenchymal transition via the Wnt–β-catenin signaling pathway","year":2019,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Wnt signaling pathway; Epithelial–mesenchymal transition; Small hairpin RNA; Cancer research; Cell migration; Gene silencing; Breast cancer; Biology; Metastasis; Long non-coding RNA; Catenin; Cell growth; Cell; Cancer; Cell biology; Signal transduction; Gene knockdown; Cell culture; Downregulation and upregulation; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008209121,0.0002397426,0.0001939471,0.0001890722,0.0001212552,0.0002035403,0.00009007091,0.0001398222,0.0007923598],"category_scores_gemma":[0.00007372465,0.0001216488,0.00021874,0.0001284707,0.0001249741,0.0001182865,0.0001617167,0.0003781434,0.0002070286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001670918,"about_ca_system_score_gemma":0.0001292798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003993189,"about_ca_topic_score_gemma":0.0008824529,"domain_scores_codex":[0.9998995,0.00001063293,0.000009380906,0.00001919874,0.00003631889,0.00002489995],"domain_scores_gemma":[0.9999462,0.00000949797,0.0000168842,0.00000545176,0.000007687348,0.00001420683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004330416,0.00001107602,0.0002020382,0.00003401995,0.000004218647,0.0000373865,0.00001028079,0.00003383805,0.9982673,0.0000292297,0.00003928083,0.001288024],"study_design_scores_gemma":[0.00001639381,0.0002630159,0.014183,0.000006475717,0.00002691182,0.0002606912,0.00003459486,0.001061432,0.9813221,0.00003984675,0.002779676,0.000005969285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919934,0.003527793,0.00232395,0.0001014506,0.00003123583,0.00002222413,0.0003593116,0.0001404569,0.001500092],"genre_scores_gemma":[0.9954795,0.001295389,0.0009941842,0.0000693533,0.000009875557,0.00002628188,0.0004601403,0.00001314957,0.001652169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007923598,"threshold_uncertainty_score":0.002650678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005600929713727777,"score_gpt":0.2170817304934941,"score_spread":0.2114808007797664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}