{"id":"W2914780443","doi":"10.1126/science.aau9072","title":"Choline acetyltransferase–expressing T cells are required to control chronic viral infection","year":2019,"lang":"en","type":"article","venue":"Science","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":158,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto; Hospital for Sick Children; Princess Margaret Cancer Centre; University Health Network","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Choline acetyltransferase; Virology; Viral infection; Acetyltransferase; Chronic infection; Biology; Chemistry; Immunology; Virus; Biochemistry; Immune system; Acetylcholine; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001980512,0.0003804998,0.0003108383,0.0002365692,0.0002514194,0.0006434283,0.0002657669,0.0005648553,0.002075688],"category_scores_gemma":[0.0004713986,0.0002008203,0.0002334156,0.0001291346,0.0004918972,0.0003454318,0.0004554891,0.001915797,0.0009812406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003996537,"about_ca_system_score_gemma":0.0002793688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005801934,"about_ca_topic_score_gemma":0.0006629896,"domain_scores_codex":[0.9997475,0.00003976724,0.00002667784,0.0000445654,0.00005473661,0.00008676451],"domain_scores_gemma":[0.9995618,0.00005210334,0.0001066746,0.00006456388,0.00006823735,0.0001465641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003044826,0.00003228557,0.0009098196,0.0000641946,0.00001572525,0.0003173386,0.00003802712,0.00006100366,0.9907975,0.0005704546,0.0006022157,0.006286945],"study_design_scores_gemma":[0.0002195849,0.0009148344,0.03957466,0.00008814891,0.00009172096,0.003294261,0.000320787,0.001862662,0.9109108,0.001900409,0.04078346,0.00003853549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9640594,0.01578619,0.006965208,0.001890086,0.0007547842,0.00008172646,0.0006866348,0.0006078405,0.009168074],"genre_scores_gemma":[0.9903204,0.002571311,0.001601168,0.0003923204,0.0001153951,0.0000396152,0.0003587556,0.0000656491,0.004535441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002075688,"threshold_uncertainty_score":0.006943941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003896602355096526,"score_gpt":0.2312343968822134,"score_spread":0.2273377945271169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}