{"id":"W2914817035","doi":"10.1107/s0108767318097209","title":"DNA damage repair – investigating the conformations of DNA ligase and PCNA","year":2018,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations and Advances","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"DNA ligase; Proliferating cell nuclear antigen; DNA; DNA repair; DNA damage; DNA Ligases; Chemistry; Molecular biology; Computational biology; Genetics; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000214193,0.0001053372,0.00009101376,0.00008525405,0.0004702531,0.00004790695,0.00007553339,0.00006653568,0.00001437524],"category_scores_gemma":[0.0001547241,0.00008358416,0.00005332626,0.000244517,0.000638182,0.00004820294,0.00007709255,0.00006504817,1.326474e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000313643,"about_ca_system_score_gemma":0.00003159404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001683826,"about_ca_topic_score_gemma":0.0002819227,"domain_scores_codex":[0.9993135,0.00005080226,0.000218057,0.0002087767,0.00008865396,0.0001202283],"domain_scores_gemma":[0.999375,0.00003560593,0.0001552612,0.000233779,0.0001422073,0.00005815349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001203257,0.00002480309,0.00123652,0.00002655112,0.0000471805,1.278578e-7,0.0002284327,0.000003093991,0.995485,0.001685971,0.0002085449,0.001041739],"study_design_scores_gemma":[0.001061102,0.001488733,0.01714212,0.0000939455,0.0001342803,0.0001107266,0.004367325,0.001807258,0.09436938,0.008417094,0.8704795,0.0005285387],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966479,0.0001850331,0.001067989,0.0004345868,0.0001279705,0.0001868053,0.00001560266,0.00004020575,0.001293897],"genre_scores_gemma":[0.9970105,0.0004550919,0.002000637,0.0002424019,0.0001201788,0.00002804752,0.00005130266,0.000009166827,0.00008273012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9011156,"threshold_uncertainty_score":0.3616855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009830779927765388,"score_gpt":0.2541531757825252,"score_spread":0.2443223958547598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}