{"id":"W2914869441","doi":"10.1002/chin.200631122","title":"Substituted Coumarins as Potent 5‐Lipoxygenase Inhibitors.","year":2006,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis of Organic Compounds","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Arachidonate 5-lipoxygenase; Combinatorial chemistry; Lipoxygenase; Organic chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001268422,0.0004203542,0.0002267877,0.0003310993,0.0001721283,0.0002128074,0.0002542202,0.0002451611,0.005388942],"category_scores_gemma":[0.0000975561,0.0001210451,0.0001670107,0.0003394799,0.0001680287,0.0002748399,0.0001995414,0.0005185333,0.001486234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002730614,"about_ca_system_score_gemma":0.0001501886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005762036,"about_ca_topic_score_gemma":0.002123046,"domain_scores_codex":[0.9999421,0.00001344639,0.000002857447,0.000007958295,0.00001094492,0.00002274627],"domain_scores_gemma":[0.9999788,0.000003672901,0.000004984405,0.000002396599,0.000002655542,0.000007546338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004173275,0.0006632647,0.000494172,0.001310754,0.0001114869,0.001376548,0.0001663922,0.004109072,0.7542447,0.01146882,0.01548565,0.206396],"study_design_scores_gemma":[0.002052397,0.01020875,0.006784725,0.0002925573,0.0002935192,0.002667404,0.0001198439,0.004994414,0.7115975,0.003453955,0.2574455,0.00008943929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6792552,0.2207048,0.0164673,0.002742333,0.001732818,0.000366207,0.003022858,0.001120556,0.07458787],"genre_scores_gemma":[0.8960342,0.07230637,0.003831568,0.0004788764,0.0001812132,0.00006678258,0.001530556,0.00004223517,0.02552808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005388942,"threshold_uncertainty_score":0.01802784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008565495673542714,"score_gpt":0.2278559858233204,"score_spread":0.2192904901497777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}