{"id":"W2914906172","doi":"10.5772/intechopen.83813","title":"Integrated Biologics Manufacturing in Stirred-Suspension Bioreactor: A Stem Cell Perspective","year":2019,"lang":"en","type":"book-chapter","venue":"IntechOpen eBooks","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Johnson and Johnson","keywords":"Good manufacturing practice; Induced pluripotent stem cell; Isolation (microbiology); Cell therapy; Biotechnology; Stem cell; Computer science; Bioinformatics; Embryonic stem cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000287415,0.0007049335,0.0006200499,0.00118299,0.0002787197,0.001758975,0.0008319966,0.001039703,0.00563151],"category_scores_gemma":[0.0001592616,0.000386077,0.0006837783,0.001584384,0.0003463107,0.001665557,0.0004959801,0.001443638,0.007201894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007562886,"about_ca_system_score_gemma":0.0004177813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000411104,"about_ca_topic_score_gemma":0.0006186586,"domain_scores_codex":[0.9997293,0.0000178497,0.0000158558,0.00006344219,0.0001594944,0.00001399779],"domain_scores_gemma":[0.999931,0.0000224712,0.000008101103,0.000007100867,0.0000246477,0.000006687233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001060243,0.000226331,0.00025524,0.004246453,0.00003557236,0.000777724,0.0003236339,0.002892113,0.2765785,0.05400465,0.02704174,0.633512],"study_design_scores_gemma":[0.000008466103,0.0001889728,0.0003610523,0.0002931681,0.00003090384,0.00147962,0.00005193397,0.002463074,0.08279112,0.006074283,0.906226,0.00003136232],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01131829,0.6505498,0.1681581,0.002245336,0.005203986,0.0001755994,0.0004725059,0.001584278,0.160292],"genre_scores_gemma":[0.04476362,0.512126,0.1536895,0.001772756,0.001755702,0.0002052943,0.0009878327,0.0004215436,0.2842778],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00563151,"threshold_uncertainty_score":0.01883924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02463708751288729,"score_gpt":0.2589223165361384,"score_spread":0.2342852290232511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}