{"id":"W2914915835","doi":"10.21037/hbsn.2019.01.01","title":"Detecting donor-specific antibodies: the importance of sorting the wheat from the chaff","year":2019,"lang":"en","type":"review","venue":"HepatoBiliary Surgery and Nutrition","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; University Health Network","funders":"","keywords":"Human leukocyte antigen; Medicine; Antigen; Antibody; Immunology; Transplantation; Epitope; Computational biology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002801817,0.0006381469,0.0005714413,0.001026143,0.0004378792,0.002221756,0.0006273504,0.001493885,0.001692921],"category_scores_gemma":[0.002639853,0.0003056198,0.0003507161,0.0005869351,0.00143328,0.001870796,0.0008897269,0.001551069,0.001556209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004835086,"about_ca_system_score_gemma":0.0005566908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005476492,"about_ca_topic_score_gemma":0.0005617483,"domain_scores_codex":[0.9982679,0.0007107111,0.0001191904,0.000278064,0.0005347576,0.00008926492],"domain_scores_gemma":[0.9983314,0.0007873164,0.0002786429,0.0001662706,0.0003364506,0.00009995524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002947834,0.0001698845,0.02879935,0.002051942,0.00009707916,0.001121839,0.0005537505,0.0009582174,0.4360231,0.01459045,0.005401077,0.5099386],"study_design_scores_gemma":[0.00005091346,0.001513654,0.02840565,0.0008482499,0.0002867103,0.0246793,0.001517084,0.009335765,0.7006153,0.02878362,0.2037932,0.000170513],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.2242678,0.1935975,0.5347977,0.01334438,0.002974541,0.0004016812,0.0002237627,0.001126802,0.02926587],"genre_scores_gemma":[0.6704521,0.06554606,0.2441809,0.005973889,0.0009868761,0.0001767545,0.0002483206,0.0002154392,0.01221977],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002801817,"threshold_uncertainty_score":0.0148176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08552103252847952,"score_gpt":0.3210373237044187,"score_spread":0.2355162911759391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}