{"id":"W2914915835","doi":"10.21037/hbsn.2019.01.01","title":"Detecting donor-specific antibodies: the importance of sorting the wheat from the chaff","year":2019,"lang":"en","type":"review","venue":"HepatoBiliary Surgery and Nutrition","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; University Health Network","funders":"","keywords":"Human leukocyte antigen; Medicine; Antigen; Antibody; Immunology; Transplantation; Epitope; Computational biology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006842258,0.0003115327,0.001210672,0.00005958998,0.0002970918,0.00003782599,0.000116477,0.0001583164,0.00003945416],"category_scores_gemma":[0.00005462439,0.0001285603,0.0006808361,0.0002488989,0.0001307277,0.00008544648,0.00002712841,0.0003768264,0.00001315552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003396984,"about_ca_system_score_gemma":0.00007122407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000944049,"about_ca_topic_score_gemma":0.0000281703,"domain_scores_codex":[0.9980458,0.000307631,0.0008366012,0.00034302,0.0002490266,0.0002179272],"domain_scores_gemma":[0.9939303,0.004866813,0.0005683195,0.0005370512,0.00005527863,0.00004224921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002387027,0.0002650959,0.2709137,0.03387027,0.001018873,0.00008806548,0.0005003403,2.053574e-7,0.00001291905,0.00008493168,0.0007183313,0.6922886],"study_design_scores_gemma":[0.001247882,0.0001555509,0.0215247,0.1251174,0.004536419,0.000654305,0.0009633879,0.00003669146,0.0001423366,0.0003331142,0.8446993,0.0005889876],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03985374,0.9578032,0.00000936473,0.0003172718,0.0003372682,0.001418344,0.0001534539,0.0000232701,0.00008409249],"genre_scores_gemma":[0.01741727,0.9814813,0.00002320777,0.0001551304,0.0002894829,0.0001203238,0.0004417307,0.00003109535,0.00004051747],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.843981,"threshold_uncertainty_score":0.5242537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08552103252847952,"score_gpt":0.3210373237044187,"score_spread":0.2355162911759391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}