{"id":"W2915035778","doi":"10.1002/jbm4.10174","title":"Osteogenesis Imperfecta: New Perspectives From Clinical and Translational Research","year":2019,"lang":"en","type":"review","venue":"JBMR Plus","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"","keywords":"Osteogenesis imperfecta; Sclerostin; Bisphosphonate; Bone morphogenetic protein; Medicine; Bone mineral; Transforming growth factor beta; Bioinformatics; Gene; Internal medicine; Cancer research; Receptor; Biology; Genetics; Osteoporosis; Pathology; Wnt signaling pathway","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008533668,0.0003326148,0.001002216,0.000178062,0.0001160603,0.00007148905,0.0004331757,0.0007295334,0.0003531342],"category_scores_gemma":[0.000671858,0.0002972442,0.0004674185,0.0002477789,0.0003312597,0.00000462117,0.0003462964,0.0006806573,0.000222838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000394551,"about_ca_system_score_gemma":0.002008516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003295167,"about_ca_topic_score_gemma":0.0001897692,"domain_scores_codex":[0.9965729,0.0009308991,0.0004478292,0.001174679,0.00043926,0.0004345041],"domain_scores_gemma":[0.998222,0.0005811967,0.00008930293,0.0006550939,0.0002334414,0.0002189707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001001419,0.0000529064,0.0002766482,0.0009127317,0.0004768732,0.000007578861,0.0001591833,4.184725e-7,0.0001073157,0.0001292881,0.00582617,0.9919508],"study_design_scores_gemma":[0.0007523819,0.0002708138,0.0003779386,0.0004741949,0.000156661,0.00001177404,0.0001909078,0.000005762166,0.00001639035,0.0001245156,0.9972822,0.0003364257],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001468207,0.9956009,0.00005198656,0.0001314564,0.000151776,0.001066111,0.0002215744,0.000009939679,0.001298017],"genre_scores_gemma":[0.0004883853,0.993194,0.0001579768,0.00001092079,0.001220053,0.00006323648,0.0006624655,0.00007841721,0.004124586],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9916143,"threshold_uncertainty_score":0.999948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2680265022520538,"score_gpt":0.5247305572082538,"score_spread":0.2567040549562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}