{"id":"W2915035778","doi":"10.1002/jbm4.10174","title":"Osteogenesis Imperfecta: New Perspectives From Clinical and Translational Research","year":2019,"lang":"en","type":"review","venue":"JBMR Plus","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"","keywords":"Osteogenesis imperfecta; Sclerostin; Bisphosphonate; Bone morphogenetic protein; Medicine; Bone mineral; Transforming growth factor beta; Bioinformatics; Gene; Internal medicine; Cancer research; Receptor; Biology; Genetics; Osteoporosis; Pathology; Wnt signaling pathway","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003049974,0.001142472,0.002295223,0.00353329,0.0005203499,0.002392055,0.001401921,0.002580179,0.005863059],"category_scores_gemma":[0.003200759,0.0003284433,0.0008095815,0.002881025,0.0015813,0.003957044,0.001491761,0.005370273,0.002355118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001600264,"about_ca_system_score_gemma":0.002719467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007663294,"about_ca_topic_score_gemma":0.001448981,"domain_scores_codex":[0.9993019,0.0001812222,0.00009850886,0.00009991187,0.00024829,0.00007019803],"domain_scores_gemma":[0.9972571,0.001557933,0.0001754187,0.00007655529,0.0006351601,0.0002977804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001807753,0.0001115232,0.0001700497,0.01580921,0.00008615891,0.0004290645,0.0001187712,0.0003145444,0.0008769693,0.01381398,0.1197086,0.8483804],"study_design_scores_gemma":[0.00003684048,0.0000976122,0.0003481622,0.005370928,0.00006231269,0.0009345786,0.00009359,0.00007482531,0.00009030666,0.006445035,0.9864264,0.00001944891],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003807825,0.9965971,0.00007098116,0.001812044,0.0009743198,0.000002186592,0.00000739068,0.000007603022,0.0004904219],"genre_scores_gemma":[0.000551147,0.99577,0.0001820945,0.001355108,0.001693007,0.000007019742,0.0000223339,0.00000268225,0.0004166267],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005863059,"threshold_uncertainty_score":0.01961392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2680265022520538,"score_gpt":0.5247305572082538,"score_spread":0.2567040549562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}