{"id":"W2915086977","doi":"10.1186/s12935-019-0745-x","title":"Low-dose zoledronate for the treatment of bone metastasis secondary to prostate cancer","year":2019,"lang":"en","type":"article","venue":"Cancer Cell International","topic":"Bone health and treatments","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"McGill University Health Centre; Mitacs; McGill University; AO North America","keywords":"Prostate cancer; Medicine; Bone metastasis; Metastasis; Prostate; Cancer research; Cell growth; Zoledronic acid; Cell; Osteolysis; Cancer; Viability assay; Cell culture; Oncology; Internal medicine; Surgery; Chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005062587,0.0001246604,0.0002308995,0.00004658153,0.00003470882,0.000007831433,0.00006339732,0.00002933066,0.00233204],"category_scores_gemma":[0.000003767718,0.00007895433,0.0001239466,0.00005566709,0.00002101631,0.00005074178,0.00001357422,0.00004070726,0.00004578472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005111548,"about_ca_system_score_gemma":0.0003371881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002241294,"about_ca_topic_score_gemma":0.0006809769,"domain_scores_codex":[0.9991671,0.000007909754,0.0002355311,0.0002099752,0.0001912293,0.000188181],"domain_scores_gemma":[0.9993655,0.00006289391,0.0001062423,0.000177282,0.0001751163,0.0001129739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.009851237,0.00336047,0.1083122,0.001016552,0.003365144,0.00003304341,0.005029808,0.001723407,0.01253785,0.000359851,0.01702854,0.8373819],"study_design_scores_gemma":[0.01660036,0.002057908,0.05983641,0.000231103,0.000533113,0.000009314292,0.0002457032,0.001545497,0.09494884,0.00006371182,0.823703,0.0002250492],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9723628,0.01078128,0.0000620746,0.006842916,0.002047672,0.002678721,0.001362147,0.00002134598,0.003841076],"genre_scores_gemma":[0.9575097,0.004166305,0.0003926868,0.001392594,0.000145672,0.001461542,0.00009426283,0.00002537935,0.03481185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8371568,"threshold_uncertainty_score":0.99858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02168722318832771,"score_gpt":0.336335949922013,"score_spread":0.3146487267336853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}