{"id":"W2915144541","doi":"10.1158/1538-7445.am2017-3020","title":"Abstract 3020: Novel therapeutic targets in head and neck cancer","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Society for Digital Humanities; Oakville-Trafalgar Memorial Hospital","funders":"","keywords":"Notch signaling pathway; Cancer research; Metastasis; Biology; Cancer; Gene knockdown; Primary tumor; Exome; Head and neck squamous-cell carcinoma; Exome sequencing; Phenotype; Medicine; Gene; Head and neck cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002097077,0.0004780411,0.0005570392,0.0004508305,0.0002075658,0.0005698715,0.000378143,0.000588078,0.004444998],"category_scores_gemma":[0.00008594999,0.0001238703,0.0004286203,0.0003061786,0.0001810262,0.0002501379,0.0003258835,0.0008279707,0.001542496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005276026,"about_ca_system_score_gemma":0.0004522729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007234752,"about_ca_topic_score_gemma":0.002469115,"domain_scores_codex":[0.9999123,0.00001146739,0.000005630734,0.0000163023,0.00003166839,0.00002261801],"domain_scores_gemma":[0.999961,0.000003629444,0.000008038232,0.000003112749,0.000009290641,0.00001491574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009002701,0.0009604726,0.000927076,0.00131243,0.0001004666,0.0006897063,0.00006579739,0.00136817,0.8711504,0.001725421,0.009875334,0.1109244],"study_design_scores_gemma":[0.001138498,0.009932914,0.01510146,0.0004084533,0.0004057426,0.004560784,0.0001576818,0.005106591,0.6373474,0.002003933,0.3237371,0.00009937063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7193621,0.2076013,0.01292091,0.003518481,0.001938879,0.001433016,0.007506064,0.001664971,0.04405423],"genre_scores_gemma":[0.8689871,0.07880983,0.008293584,0.002004647,0.0002671649,0.0006863843,0.009824644,0.0001479645,0.03097864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004444998,"threshold_uncertainty_score":0.01486999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08130814490490479,"score_gpt":0.431219271890472,"score_spread":0.3499111269855673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}