{"id":"W2915318641","doi":"10.1016/j.cell.2019.01.051","title":"SnapShot: Cancer Immunotherapy with Oncolytic Viruses","year":2019,"lang":"en","type":"article","venue":"Cell","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; Ontario Institute for Cancer Research; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Oncolytic virus; Biology; Immune system; Immunotherapy; Cancer immunotherapy; Immune checkpoint; Blockade; Cancer; Immunology; Cancer research; Cancer cell; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001022913,0.0001316193,0.0001151656,0.00003072384,0.00003083968,0.00002191288,0.0002275494,0.00008252476,0.0009660112],"category_scores_gemma":[0.000002079545,0.0001053386,0.00004969633,0.00008632533,0.00005349142,0.000002556727,0.00003624619,0.00009061811,0.0001237685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002523321,"about_ca_system_score_gemma":0.0001956032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004715537,"about_ca_topic_score_gemma":0.0001610064,"domain_scores_codex":[0.9991601,0.00004168666,0.00009296532,0.0002851103,0.000153467,0.00026672],"domain_scores_gemma":[0.9993783,0.000008823225,0.00003916705,0.0004578697,0.00005621168,0.00005968706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001883575,0.00005735916,0.003417656,0.00001532193,0.00004630008,0.000002208571,0.00003637063,0.0001762375,0.9910399,0.000001738865,0.001608461,0.001714895],"study_design_scores_gemma":[0.001387366,0.002254265,0.0004063846,0.000008596514,0.000004300289,0.000002112602,0.00002615327,0.00001961819,0.8863925,0.000006789855,0.1093315,0.0001604279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990465,0.00299101,0.00002230525,0.00007129642,0.00009127972,0.0002693627,0.000008535345,0.00001635085,0.006064809],"genre_scores_gemma":[0.9929736,0.0007261777,0.00008231532,0.001095847,0.0001505934,0.00004697553,0.00002736937,0.00006299719,0.00483411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1077231,"threshold_uncertainty_score":0.9999472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01457351143039986,"score_gpt":0.2970461340474997,"score_spread":0.2824726226170998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}