{"id":"W2915484156","doi":"10.3389/fcimb.2019.00028","title":"Infectious Complications Are Associated With Alterations in the Gut Microbiome in Pediatric Patients With Acute Lymphoblastic Leukemia","year":2019,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; IWK Health Centre; Cancer Research Institute; Terry Fox Research Institute; Beatrice Hunter Cancer Research Institute; Nova Scotia Health Research Foundation","keywords":"Metagenomics; Microbiome; Lymphoblastic Leukemia; Biology; Leukemia; Immunology; Medicine; Gene; Bioinformatics; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001850905,0.0001967637,0.0002460548,0.0003186096,0.00009218962,0.0000264929,0.0001079168,0.0002385833,0.000005400505],"category_scores_gemma":[0.00001638441,0.0001490924,0.00003213124,0.0004788559,0.00009942149,0.00001440104,0.00003863358,0.0002309224,0.0000070863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001779239,"about_ca_system_score_gemma":0.000136752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001330163,"about_ca_topic_score_gemma":0.001858337,"domain_scores_codex":[0.998735,0.0002146323,0.0002802686,0.0004123408,0.00003306706,0.0003247559],"domain_scores_gemma":[0.9994878,0.00002389643,0.000156744,0.0002304222,0.00006858536,0.00003256578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007638574,0.0002171394,0.9115868,0.00002100527,0.0000307806,0.000002629489,0.000126739,0.0002765773,0.08690563,0.00000841905,0.0007143355,0.00003353982],"study_design_scores_gemma":[0.00372306,0.0005703036,0.992899,0.00003873,0.0000340689,0.00003311627,0.00005905572,0.00005402172,0.0008143809,0.00001678625,0.001506472,0.0002510181],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973379,0.0002175129,0.001269997,0.00006624102,0.0002255857,0.0006641081,0.00005739936,0.00000944259,0.0001517951],"genre_scores_gemma":[0.9980604,0.0001942681,0.0001417928,0.0003444893,0.00002795188,0.00004704153,0.001090397,0.00001816139,0.00007549155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08609125,"threshold_uncertainty_score":0.6079811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003143028399629418,"score_gpt":0.1926286290505787,"score_spread":0.1894856006509493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}