{"id":"W2915537626","doi":"10.1016/j.carbpol.2019.02.080","title":"Xylose rich heteroglycan from flaxseed gum mediates the immunostimulatory effects on macrophages via TLR2 activation","year":2019,"lang":"en","type":"article","venue":"Carbohydrate Polymers","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"National Key Research and Development Program of China; Chinese Universities Scientific Fund; National Natural Science Foundation of China","keywords":"TLR2; p38 mitogen-activated protein kinases; Chemistry; Phosphorylation; Kinase; Tumor necrosis factor alpha; Signal transduction; Biochemistry; Protein kinase A; Biology; TLR4; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013111,0.0002624151,0.0002408296,0.00002165158,0.0002071793,0.00009435661,0.0004047559,0.0001421756,0.0006325673],"category_scores_gemma":[0.00002706084,0.00009342531,0.0001262756,0.0002689336,0.00005203889,0.0001282256,0.00006954055,0.0002247388,0.0004396869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003944761,"about_ca_system_score_gemma":0.000008742529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002298527,"about_ca_topic_score_gemma":0.00006554038,"domain_scores_codex":[0.9985658,0.0001586851,0.0002076747,0.0003829632,0.0002764337,0.0004084696],"domain_scores_gemma":[0.9983881,0.001170287,0.0001393618,0.0001644447,0.00002314434,0.0001146915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007269123,0.00002423249,0.001825585,0.000004530736,0.00004957051,0.000005285995,0.0001191409,0.00002994024,0.9706093,0.00001069109,0.0001236258,0.02712543],"study_design_scores_gemma":[0.0002660232,0.0002541032,0.06173338,0.00004710247,0.00003166401,9.254057e-7,0.00009452029,0.0007352169,0.9354486,0.000133154,0.0009598156,0.0002955001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963104,0.0006932291,6.990112e-7,0.0008791425,0.0008731776,0.000380861,0.00007654927,0.00008188446,0.0007041256],"genre_scores_gemma":[0.9975237,0.00005443688,0.000002821128,0.001316422,0.0003995789,0.00001779086,0.0002146479,0.000003809474,0.0004667803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0599078,"threshold_uncertainty_score":0.6926169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006125442571216608,"score_gpt":0.186358957104157,"score_spread":0.1802335145329404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}