{"id":"W2915663078","doi":"10.1182/blood-2018-99-119734","title":"Functional and Molecular Consequences of Trisomy 21 on Human Fetal Hematopoiesis","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Biology; Haematopoiesis; Trisomy; Bone marrow; Progenitor cell; Immunology; Leukemia; Fetus; Flow cytometry; Transplantation; Stem cell; Andrology; Molecular biology; Cancer research; Genetics; Internal medicine; Medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001255098,0.0001502063,0.00007971617,0.0003354698,0.0001122035,0.0002121186,0.00008994989,0.0001482054,0.001504916],"category_scores_gemma":[0.0002054474,0.00007839414,0.00009644926,0.0001877101,0.0001871417,0.00007569875,0.0002054505,0.0001984656,0.0001883973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002215273,"about_ca_system_score_gemma":0.0001284309,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001979506,"about_ca_topic_score_gemma":0.001271953,"domain_scores_codex":[0.9998822,0.00002251032,0.00001064102,0.0000267203,0.00003361531,0.00002430724],"domain_scores_gemma":[0.9999007,0.00003087605,0.00002703339,0.00001134105,0.00001262238,0.00001743792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001754658,0.000006995218,0.005839417,0.00001996722,0.000005910123,0.0002404194,0.00004654661,0.0001710113,0.9906043,0.00009320902,0.00004888073,0.002747805],"study_design_scores_gemma":[0.000008208166,0.0003339495,0.235971,0.00001058951,0.00003064681,0.002096208,0.0001733194,0.00138367,0.7571493,0.000130729,0.002701622,0.00001073198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975299,0.0003646793,0.0006658327,0.00004150067,0.000003834896,0.000007007051,0.0007100719,0.00002620841,0.0006509601],"genre_scores_gemma":[0.9984509,0.0002348454,0.0004200821,0.00001691115,0.000001717657,0.000006269916,0.0005015897,0.000007958502,0.0003596445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001979506,"threshold_uncertainty_score":0.005034506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02860312171328101,"score_gpt":0.2797724438841057,"score_spread":0.2511693221708247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}