{"id":"W2915698847","doi":"10.1016/j.clinthera.2019.01.017","title":"A Single-dose, Comparative Bioavailability Study of a Formulation containing OM3 as Phospholipid and Free Fatty Acid to an Ethyl Ester Formulation in the Fasting and Fed States","year":2019,"lang":"en","type":"article","venue":"Clinical Therapeutics","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University; Supratek Pharma (Canada); Pharma Medica Research (Canada); BioPhage Pharma (Canada)","funders":"Regeneron Pharmaceuticals; Sanofi; Aegerion Pharmaceuticals; Amgen","keywords":"Bioavailability; Medicine; Cmax; Docosahexaenoic acid; Meal; Pharmacokinetics; Crossover study; Eicosapentaenoic acid; Fatty acid; Pharmacology; Food science; Internal medicine; Chemistry; Biochemistry; Polyunsaturated fatty acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001957437,0.001105368,0.003074909,0.001084287,0.0008941269,0.001044549,0.001186621,0.001695432,0.003840339],"category_scores_gemma":[0.002394637,0.0009354678,0.00185169,0.0008346428,0.00182855,0.001907814,0.000440664,0.002918363,0.0007742529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007510268,"about_ca_system_score_gemma":0.001314561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002744073,"about_ca_topic_score_gemma":0.002318811,"domain_scores_codex":[0.9990132,0.0003616083,0.00007883496,0.0002694625,0.0001383763,0.000138456],"domain_scores_gemma":[0.9977133,0.0007973682,0.0004129408,0.0002942858,0.0002968076,0.0004851814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7761055,0.07816216,0.0007478263,0.0004709034,0.0004059558,0.0001824767,0.0003401527,0.0005125873,0.1282821,0.0002430927,0.0004111061,0.01413617],"study_design_scores_gemma":[0.04228092,0.9054518,0.006690414,0.00002238642,0.00077364,0.0001322769,0.0002275563,0.001075207,0.04208881,0.0001136932,0.001072533,0.0000708712],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972944,0.0003721454,0.0006931387,0.0000755985,0.0001583216,0.0005066216,0.0002946884,0.00003603077,0.0005689336],"genre_scores_gemma":[0.9919669,0.000799905,0.002112378,0.000255648,0.0002246052,0.0005363211,0.0005215295,0.00005518125,0.003527595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003840339,"threshold_uncertainty_score":0.01284719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2273195481318258,"score_gpt":0.4593779968017172,"score_spread":0.2320584486698914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}