{"id":"W2915719692","doi":"10.21037/jtd.2019.01.74","title":"Association of the TLR1 variant rs5743557 with susceptibility to tuberculosis","year":2019,"lang":"en","type":"article","venue":"Journal of Thoracic Disease","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Specialized Research Fund for the Doctoral Program of Higher Education of China; National Natural Science Foundation of China","keywords":"Medicine; Tuberculosis; Multifactor dimensionality reduction; Linkage disequilibrium; Mycobacterium tuberculosis; Genotype; Immunology; Haplotype; Internal medicine; Gene; Genetics; Single-nucleotide polymorphism; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001838495,0.0001071658,0.0004395047,0.0001187776,0.00003523294,0.00001147215,0.000200482,0.00006279036,0.000364689],"category_scores_gemma":[0.003095189,0.0000558012,0.000289426,0.0003242212,0.00003776421,0.0001118863,0.00006516345,0.0003296998,0.00004933096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002385479,"about_ca_system_score_gemma":0.0004112682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003344562,"about_ca_topic_score_gemma":0.0000225137,"domain_scores_codex":[0.9979719,0.0003974666,0.0004781175,0.0001503356,0.0007326007,0.0002695893],"domain_scores_gemma":[0.9977411,0.0002909389,0.000407512,0.0004262112,0.0005825195,0.0005517253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003356691,0.0003735876,0.9812964,0.0002915158,0.0003861535,0.00004397208,0.00008323927,0.0002223514,0.002984139,0.00003622343,0.009317257,0.001608453],"study_design_scores_gemma":[0.0005343087,0.0006587944,0.9951935,0.0004013635,0.0004893722,0.00004381832,0.00008453304,0.0001194732,0.0006814869,0.0001677735,0.001556686,0.00006892093],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9652291,0.0001629379,0.00007114995,0.03334919,0.000172364,0.00037011,0.00002101226,0.000005269293,0.0006188785],"genre_scores_gemma":[0.9968032,0.00004156403,0.0004455929,0.001367436,0.0001543619,0.000003138502,0.000002004479,0.0000120372,0.001170712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03198175,"threshold_uncertainty_score":0.3993089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01345684415688228,"score_gpt":0.3348303317235345,"score_spread":0.3213734875666522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}