{"id":"W2915965247","doi":"10.25376/hra.7276502","title":"Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia","year":2018,"lang":"en","type":"book-chapter","venue":"Figshare","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fogarty International Center; Canadian Institute for Advanced Research; Cincinnati Children's Hospital Medical Center; Doris Duke Charitable Foundation","keywords":"Malaria; Medicine; Placebo; Sickle cell anemia; Anemia; Fetal hemoglobin; Internal medicine; Incidence (geometry); Parasitemia; Neutropenia; Adverse effect; Pediatrics; Immunology; Chemotherapy; Plasmodium falciparum; Pregnancy; Biology; Pathology; Fetus; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00004060503,0.0004320774,0.00070656,0.0002232653,0.00004466406,0.00002636998,0.000161119,0.0006858771,0.009175263],"category_scores_gemma":[0.0000750748,0.0003056622,0.0001399052,0.00008902229,0.00005526884,0.0001159459,0.00004362474,0.0004904828,0.00005350458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007265557,"about_ca_system_score_gemma":0.000403805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004908479,"about_ca_topic_score_gemma":0.000154896,"domain_scores_codex":[0.9984249,0.00001036609,0.0003857943,0.0005428155,0.0003117372,0.0003243738],"domain_scores_gemma":[0.9984846,0.00006199982,0.0004364497,0.000573482,0.0002570229,0.0001865126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.2088593,0.002468761,0.0005465829,0.004881189,0.001169098,0.0005435012,0.002975929,0.0001734606,0.0002380266,0.0003797183,0.7744061,0.003358292],"study_design_scores_gemma":[0.3583243,0.04989478,0.004036827,0.0502358,0.002562954,0.0008152915,0.0003358338,0.0004813429,0.0007678939,0.0001548709,0.528864,0.00352616],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.05018113,0.001553565,0.0000706407,0.001061221,0.0003409836,0.04009733,0.6029231,0.0006211172,0.3031509],"genre_scores_gemma":[0.1674808,0.00007892142,0.00273967,0.0009172324,0.001768303,0.0009487276,0.6184849,0.000956376,0.206625],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.2455422,"threshold_uncertainty_score":0.9999396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04125285090499641,"score_gpt":0.2398443977023928,"score_spread":0.1985915467973964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}