{"id":"W2916363255","doi":"10.3389/fpls.2019.00313","title":"RNA Interference in the Tobacco Hornworm, Manduca sexta, Using Plastid-Encoded Long Double-Stranded RNA","year":2019,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"Manduca sexta; Biology; RNA interference; RNA silencing; Manduca; Gene silencing; Nicotiana tabacum; Sphingidae; Plastid; RNA; Gene; Botany; Insect; Cell biology; Genetics; Chloroplast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009812541,0.0002944373,0.0001442546,0.0001330193,0.0001330377,0.0002107148,0.0001470863,0.0002724392,0.0004812679],"category_scores_gemma":[0.00009237215,0.00013774,0.0002496397,0.00008405117,0.0001537567,0.0001114944,0.0001309362,0.0003118668,0.000155741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002402259,"about_ca_system_score_gemma":0.0001308166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007061017,"about_ca_topic_score_gemma":0.001626864,"domain_scores_codex":[0.9999086,0.00001065967,0.00001125546,0.0000322402,0.00002579484,0.00001159486],"domain_scores_gemma":[0.9999372,0.0000124138,0.00002594392,0.000006857621,0.000007699634,0.000009868571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009578196,0.000004658399,0.0001282039,0.0000200989,0.000002388626,0.0000131209,0.000004307772,0.00001070583,0.9995362,0.00001496894,0.000004128085,0.0002516959],"study_design_scores_gemma":[0.0000111111,0.0003160293,0.006827912,0.000007038871,0.00003671215,0.0001471386,0.00001824225,0.0004236308,0.9909258,0.00001679388,0.001267332,0.000002307474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954105,0.001190651,0.002126784,0.00005502412,0.00002391111,0.00002892133,0.0002465147,0.00004926022,0.0008684172],"genre_scores_gemma":[0.9905332,0.001054839,0.004497797,0.00006707538,0.00000770031,0.00004669546,0.0006054218,0.00001680009,0.003170466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007061017,"threshold_uncertainty_score":0.001742959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360677607450414,"score_gpt":0.245667438207774,"score_spread":0.2320606621332698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}