{"id":"W2916363255","doi":"10.3389/fpls.2019.00313","title":"RNA Interference in the Tobacco Hornworm, Manduca sexta, Using Plastid-Encoded Long Double-Stranded RNA","year":2019,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"Manduca sexta; Biology; RNA interference; RNA silencing; Manduca; Gene silencing; Nicotiana tabacum; Sphingidae; Plastid; RNA; Gene; Botany; Insect; Cell biology; Genetics; Chloroplast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006127602,0.0001671589,0.000170302,0.0001616255,0.0001061978,0.00009366076,0.0008585261,0.0001081482,0.000007901971],"category_scores_gemma":[0.00002480652,0.0001289302,0.00004070955,0.000454998,0.0002564034,0.0000232393,0.0001061446,0.000201298,0.000005621876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005899171,"about_ca_system_score_gemma":0.0002513679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006502866,"about_ca_topic_score_gemma":0.0004532081,"domain_scores_codex":[0.9984655,0.00004469929,0.0002401528,0.0004810511,0.0002823686,0.0004862091],"domain_scores_gemma":[0.9994068,0.0000129966,0.000077727,0.0004100811,0.00003833757,0.00005403508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006621638,0.0001064131,0.2864484,0.00003770947,0.0000154803,0.00005314318,0.001064227,0.003178102,0.7043449,0.00006455379,0.002070573,0.001954286],"study_design_scores_gemma":[0.004884202,0.0006869237,0.1279559,0.000452647,0.00003083425,0.0001520369,0.004404685,0.009294266,0.847856,0.0004219185,0.002532043,0.00132852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992642,0.0003438274,0.003437414,0.00004147744,0.0009682908,0.0002829782,0.00001819728,0.000004745742,0.002261062],"genre_scores_gemma":[0.9977869,0.000139013,0.001619338,0.0001584743,0.00006546246,0.000008188073,0.00002064894,0.000007747979,0.000194276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1584925,"threshold_uncertainty_score":0.5257623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360677607450414,"score_gpt":0.245667438207774,"score_spread":0.2320606621332698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}