{"id":"W2916717962","doi":"10.1001/jamacardio.2019.0014","title":"Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial","year":2019,"lang":"en","type":"article","venue":"JAMA Cardiology","topic":"Cardiac Imaging and Diagnostics","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Canadian Heart Research Centre; University of Toronto","funders":"Duke Clinical Research Institute; National Heart, Lung, and Blood Institute; Abbott Vascular; Sirtex Medical; Merck Sharp and Dohme; KU Leuven; University of Toronto; Institut de Cardiologie de Montréal; Heart and Stroke Foundation of Canada; Henry Ford Health System; Tenax Therapeutics; David Geffen School of Medicine, University of California, Los Angeles; Massachusetts General Hospital; Luitpold Pharmaceuticals; Perelman School of Medicine, University of Pennsylvania; Vanderbilt University Medical Center; Dalio Foundation; Cedars-Sinai Medical Center; National Institutes of Health; Regeneron Pharmaceuticals; Arbor Pharmaceuticals; University of Hull; Amgen; Daiichi Sankyo Europe; Servier; Gilead Sciences; Vanderbilt University; Daiichi-Sankyo; York University; Pfizer; Omron Healthcare; Sanofi; Weill Cornell Medical College; CSL Behring; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Randomized controlled trial; Coronary artery disease; Revascularization; Internal medicine; Ischemia; Stenosis; Cardiology; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01400965,0.0008378269,0.001626606,0.0005474044,0.0006199538,0.001139168,0.000641174,0.001741462,0.005257442],"category_scores_gemma":[0.0200505,0.0004349428,0.001544617,0.0008908941,0.0008560838,0.001345323,0.0003993884,0.001622012,0.0007159298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004035893,"about_ca_system_score_gemma":0.001080513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002313474,"about_ca_topic_score_gemma":0.0003841551,"domain_scores_codex":[0.9877319,0.007868473,0.001492208,0.001120606,0.00115706,0.000629621],"domain_scores_gemma":[0.9942947,0.002656805,0.00165526,0.0006155146,0.0003411809,0.0004365462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6125948,0.007593059,0.2895376,0.002866399,0.007722609,0.0006729261,0.0007353366,0.001666637,0.002696884,0.003121764,0.01315886,0.05763311],"study_design_scores_gemma":[0.4331957,0.09380361,0.4007251,0.001934917,0.01123289,0.001481465,0.0008599736,0.009315264,0.00358783,0.01565391,0.02791956,0.0002898619],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9380383,0.01090346,0.007177207,0.003636515,0.0007085841,0.01770148,0.01302679,0.00009885751,0.008708618],"genre_scores_gemma":[0.964506,0.0008489007,0.003783996,0.002699964,0.0002316798,0.02260856,0.003741024,0.00001989975,0.00156002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01400965,"threshold_uncertainty_score":0.07409102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03529136860414043,"score_gpt":0.3502187615502118,"score_spread":0.3149273929460714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}