{"id":"W2917312653","doi":"10.1002/jsde.12266","title":"Systemic Concocting of Cross‐Linked Enzyme Aggregates of <i>Candida antarctica</i> Lipase B (Novozyme 435) for the Biomanufacturing of Rhamnolipids","year":2019,"lang":"en","type":"article","venue":"Journal of Surfactants and Detergents","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Materium Innovations (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Lipase; Candida antarctica; Glutaraldehyde; Immobilized enzyme; Chromatography; Triacylglycerol lipase; Yield (engineering); Enzyme assay; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004434172,0.000126234,0.0003787186,0.00006094583,0.00004065561,0.00001524374,0.0001727201,0.00009782329,0.00001303016],"category_scores_gemma":[0.0001239788,0.00008317238,0.0001948119,0.00007155661,0.0000917005,0.00002203298,0.00006041272,0.00005900327,2.241696e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009296033,"about_ca_system_score_gemma":0.00005838344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002135394,"about_ca_topic_score_gemma":0.000003717741,"domain_scores_codex":[0.9987214,0.00002805207,0.0007869219,0.0001391291,0.0001799774,0.0001445499],"domain_scores_gemma":[0.9981374,0.00009200293,0.001122405,0.0002090122,0.0003861409,0.00005305801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000356134,0.00004733768,0.07642089,0.0002729807,0.0002338748,4.648246e-7,0.0001029759,0.00028983,0.9215077,0.000003138351,0.00002529957,0.0007393942],"study_design_scores_gemma":[0.001342807,0.0005445377,0.009926168,0.0002545763,0.00009725147,0.00004098441,0.0002121532,0.0003033598,0.9868951,0.00001010408,0.0002831029,0.0000898956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950339,0.004020524,0.0003298944,0.00001006532,0.000339668,0.000189787,0.00006039454,0.000001040258,0.00001476853],"genre_scores_gemma":[0.9983265,0.001360577,0.0001481826,0.00001770656,0.00007182865,0.000001272369,0.00001083843,0.00001463361,0.00004849241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06649472,"threshold_uncertainty_score":0.3391671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01204536307910622,"score_gpt":0.2706736701901356,"score_spread":0.2586283071110294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}