{"id":"W2917317549","doi":"10.1080/15476286.2019.1582955","title":"La proteins couple use of sequence-specific and non-specific binding modes to engage RNA substrates","year":2019,"lang":"en","type":"review","venue":"RNA Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Institute of Genetics; Canadian Institutes of Health Research","keywords":"Biology; RNA-binding protein; Sequence (biology); RNA; Genetics; Computational biology; Evolutionary biology; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005726293,0.0005378468,0.001339236,0.000201609,0.00009083693,0.00005671338,0.0004487389,0.001081734,0.00004203356],"category_scores_gemma":[0.00008261988,0.0004353516,0.0002999354,0.0001798241,0.0001899191,0.000007794431,0.0002408151,0.0003156982,0.00006212874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003073347,"about_ca_system_score_gemma":0.0001361807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002526469,"about_ca_topic_score_gemma":0.000005999427,"domain_scores_codex":[0.9974461,0.0004845369,0.0006264937,0.0008919449,0.0001014628,0.0004494513],"domain_scores_gemma":[0.9984333,0.0002045537,0.0004023466,0.0007394922,0.00008190732,0.0001384332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002993535,0.0000266343,0.000007051818,0.001220339,0.0001043504,0.000006115367,0.00001974947,0.000001853817,0.6851138,0.0005249892,0.000131118,0.3128141],"study_design_scores_gemma":[0.000148057,0.0004122285,0.000003626143,0.001420578,0.00006535066,0.00003749987,0.00002231582,0.000002087904,0.1394756,0.00004236968,0.8578911,0.0004792365],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04913689,0.9469368,0.00119161,0.00001188437,0.0002185372,0.001732917,0.0004530135,0.00001732175,0.0003009553],"genre_scores_gemma":[0.02663627,0.9685303,0.003586106,0.00001757068,0.0001707734,0.0002206454,0.0004009703,0.00008237195,0.0003549733],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.85776,"threshold_uncertainty_score":0.9998098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1230180440545382,"score_gpt":0.3244448734293766,"score_spread":0.2014268293748385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}