{"id":"W2917321490","doi":"10.1016/j.ejca.2019.01.017","title":"Neurotoxicity induced by targeted therapies in patients treated for metastatic melanoma","year":2019,"lang":"en","type":"letter","venue":"European Journal of Cancer","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Vemurafenib; Dabrafenib; Trametinib; Medicine; Melanoma; Internal medicine; Oncology; Rash; Dermatology; Cancer research; Metastatic melanoma; MAPK/ERK pathway; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003312533,0.0002157485,0.0007295349,0.0003427455,0.0006206867,0.0005628481,0.0002713444,0.001498693,0.001407426],"category_scores_gemma":[0.002369767,0.000125775,0.0006156863,0.0007069178,0.0002273113,0.0002663036,0.0002420004,0.001537618,0.0002434911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00136636,"about_ca_system_score_gemma":0.0005285114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001857948,"about_ca_topic_score_gemma":0.00405874,"domain_scores_codex":[0.9997712,0.00007967631,0.00003273988,0.00002388574,0.00003896736,0.00005355514],"domain_scores_gemma":[0.9990911,0.0003341827,0.0002427019,0.00004485096,0.0001369486,0.0001501553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01765189,0.000541907,0.5418712,0.001081297,0.0009135795,0.2154442,0.0008921289,0.00153417,0.01459758,0.002114015,0.03891122,0.1644467],"study_design_scores_gemma":[0.0009546112,0.004211979,0.7585041,0.0004664545,0.001278405,0.1706709,0.0006073471,0.002272558,0.004522656,0.004342207,0.05206696,0.0001017104],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.8715435,0.02352191,0.0009427104,0.0774531,0.002162278,0.0001159891,0.0007884363,0.0001134876,0.0233586],"genre_scores_gemma":[0.9758409,0.00422748,0.0002356617,0.01520457,0.002539853,0.00003388657,0.0001805526,0.00001513134,0.001722031],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.001857948,"threshold_uncertainty_score":0.009913683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783321065638458,"score_gpt":0.2468876863466996,"score_spread":0.2290544756903151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}