{"id":"W2917332631","doi":"10.1513/annalsats.201811-784rl","title":"Calcineurin Inhibitors and Variation in the Performance of Interferon-γ Release Assays Used to Detect Tuberculosis Infection","year":2019,"lang":"en","type":"letter","venue":"Annals of the American Thoracic Society","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; National Institute for Health and Care Research; Cancer Research UK","keywords":"Medicine; Tuberculosis; Calcineurin; Interferon γ; Interferon; Immunology; Virology; Interferon gamma; Internal medicine; Pathology; Transplantation; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004796494,0.0004613098,0.0008474612,0.0007739352,0.0007576607,0.00148137,0.0009878776,0.00640012,0.0007945732],"category_scores_gemma":[0.0378675,0.0003644773,0.0004746131,0.0008899778,0.00111071,0.000648818,0.0003034831,0.003554525,0.0006376465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002012855,"about_ca_system_score_gemma":0.0007213291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003651053,"about_ca_topic_score_gemma":0.003753056,"domain_scores_codex":[0.9901008,0.004214393,0.00166024,0.0008533447,0.002591406,0.0005798921],"domain_scores_gemma":[0.9734432,0.01857884,0.002810355,0.001080871,0.003156151,0.0009306281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003100702,0.0007578059,0.6042457,0.0003700694,0.0003929489,0.1097554,0.003497282,0.001514919,0.01575125,0.002744744,0.154743,0.1031261],"study_design_scores_gemma":[0.0004643216,0.002771738,0.5847024,0.000930985,0.0006228506,0.2350587,0.003524717,0.01377175,0.0200055,0.008095191,0.1297376,0.0003143029],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.45908,0.0108458,0.004441229,0.480556,0.01229003,0.0001206542,0.000497849,0.0003529317,0.03181542],"genre_scores_gemma":[0.8803565,0.001425714,0.001340141,0.1037737,0.009893131,0.00004507304,0.0001137249,0.00007791763,0.002974133],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.00640012,"threshold_uncertainty_score":0.02536654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07566103083259662,"score_gpt":0.3921087238326831,"score_spread":0.3164476930000865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}